Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | LIG1 | P18858 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 3/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23713624 | 0.81 | TRPA1 (0.41) | TRPA1ESR1ESR2 | |
| SCHEMBL18899507 | 0.81 | TRPA1 (0.45) | TRPA1ATMESR1ESR2 | |
| SCHEMBL23713609 | 0.81 | TRPA1 (0.41) | TRPA1ESR1ESR2 | |
| SCHEMBL8718208 | 0.81 | TRPA1 (0.61) | TRPA1 | |
| SCHEMBL8907499 | 0.79 | ESR2 (0.44) | TRPA1ATMESR1ESR2KDM1A | |
| SCHEMBL8907505 | 0.79 | ESR2 (0.44) | TRPA1ATMESR1ESR2KDM1A | |
| SCHEMBL8908135 | 0.78 | KDM1A (0.43) | TRPA1ESR1ESR2KDM1ARCOR1 | |
| SCHEMBL8907343 | 0.75 | TACR1 (0.49) | TRPA1KDM1ARCOR1 | |
| SCHEMBL353495 | 0.75 | ESR2 (0.47) | ATMESR1ESR2KDM1A | |
| SCHEMBL779666 | 0.75 | ATM (0.46) | ATMESR2KDM1APTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190343819-A1 | Opioid Receptor Ligands And Methods Of Using And Making Same | TREVENA, INC. | 2019-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190343819-A1 | Opioid Receptor Ligands And Methods Of Using And Making Same | OPRL1, OPRK1, OPRM1 | TRPA1 216/4885LIG1 4517/4885ATM 4792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.