Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 4/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KMO | O15229 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23713609 | 0.80 | TRPA1 (0.41) | TRPA1DDB1CRBNKDM4EMAPT | |
| SCHEMBL8718208 | 0.79 | TRPA1 (0.61) | TRPA1DRD2DRD3 | |
| SCHEMBL16334825 | 0.79 | HDAC4 (0.52) | DDB1CRBNHDAC4HDAC2HDAC8 | |
| SCHEMBL18956824 | 0.79 | HDAC4 (0.47) | DDB1CRBNHDAC4HDAC2HDAC8 | |
| SCHEMBL1176491 | 0.77 | KMO (0.53) | DDB1CRBNHDAC4HDAC2HDAC8 | |
| SCHEMBL6100303 | 0.77 | KMO (0.53) | DDB1CRBNHDAC4HDAC2HDAC8 | |
| Hydrochloric Acid SCHEMBL4444055 | 0.77 | HDAC4 (0.50) | DDB1CRBNHDAC4HDAC2HDAC8 | |
| SCHEMBL29933389 | 0.75 | DDB1 (0.41) | TRPA1DDB1CRBNCYP3A4CASP1 | |
| SCHEMBL23364721 | 0.75 | DDB1 (0.41) | TRPA1DDB1CRBNCYP3A4CASP1 | |
| SCHEMBL273350 | 0.74 | CYP3A4 (0.50) | DDB1CRBNHDAC4HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11077098-B2 | Opioid receptor ligands and methods of using and making same | TREVENA, INC. (US) | 2021-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11077098-B2 | Opioid receptor ligands and methods of using and making same | OPRL1, OPRK1, OPRM1 | TRPA1 216/4885DDB1 4618/4885CRBN 4498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.