Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGG1 | O15527 | 1/20 | 0.44 |
| ▸ | WDR5 | P61964 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 3/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23715916 | 0.92 | OGG1 (0.44) | OGG1WDR5ALDH1A1 | |
| SCHEMBL23716111 | 0.90 | OGG1 (0.45) | OGG1WDR5PARP1 | |
| SCHEMBL23716135 | 0.88 | KMT2A (0.37) | PARP1PPARGKMT2ACNR1POLB | |
| SCHEMBL23716330 | 0.84 | MDM2 (0.38) | PPARGFFAR1KMT2ACNR1ALDH1A1 | |
| SCHEMBL23716312 | 0.80 | S1PR3 (0.52) | — | |
| SCHEMBL23715832 | 0.79 | S1PR3 (0.58) | — | |
| SCHEMBL23716117 | 0.78 | OGG1 (0.38) | OGG1WDR5PTGER4PPARGFFAR1 | |
| SCHEMBL23715793 | 0.76 | SYK (0.45) | PARP1KMT2AALDH1A1 | |
| SCHEMBL23715975 | 0.75 | SIRT1 (0.42) | KMT2A | |
| SCHEMBL9627765 | 0.73 | OGG1 (0.51) | OGG1WDR5PARP1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209732-B1 | SPHINGOSINE-1-PHOSPATE RECEPTOR MODULATORS FOR TREATMENT OF CARDIOPULMONARY DISORDERS | SCRIPPS RESEARCH INST (US) | 2021-08-04 | — | — | EP | disclosed |