Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | KDM5A | P29375 | 2/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.35 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.32 |
| ▸ | MAP4K1 | Q92918 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17663978 | 0.86 | TSHR (0.42) | CYP3A4KDM5AKDM5BKMT2AALDH1A1 | |
| SCHEMBL23716376 | 0.79 | L3MBTL1 (0.36) | KDM4EKDM5AKDM5BALDH1A1KDM4A | |
| SCHEMBL17663981 | 0.79 | GPR52 (0.38) | CYP3A4KDM5AKDM5BKMOMAPT | |
| SCHEMBL12107538 | 0.74 | CYP3A4 (0.54) | CYP3A4KDM4ELMNAALDH1A1NPSR1 | |
| SCHEMBL23716203 | 0.72 | MBOAT4 (0.39) | CYP3A4KDM4ELMNAALDH1A1NPSR1 | |
| SCHEMBL23716445 | 0.72 | KEAP1 (0.38) | CYP3A4KDM4ELMNAALDH1A1NPSR1 | |
| SCHEMBL12706760 | 0.69 | CYP3A4 (0.48) | CYP3A4KDM4ELMNAALDH1A1NPSR1 | |
| SCHEMBL12607303 | 0.68 | CYP3A4 (0.77) | CYP3A4KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL168931 | 0.68 | — | — | |
| SCHEMBL28233999 | 0.68 | SLC6A2 (0.43) | CYP3A4KDM5AKDM5BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209732-B1 | SPHINGOSINE-1-PHOSPATE RECEPTOR MODULATORS FOR TREATMENT OF CARDIOPULMONARY DISORDERS | SCRIPPS RESEARCH INST (US) | 2021-08-04 | — | — | EP | disclosed |