Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.32 |
| ▸ | MAP4K1 | Q92918 | 3/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
| ▸ | KDM4A | O75164 | 2/20 | 0.32 |
| ▸ | KDM5A | P29375 | 2/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17663978 | 0.83 | TSHR (0.42) | IDO1ALDH1A1KDM4AKDM5AKDM5B | |
| SCHEMBL23716473 | 0.79 | CYP3A4 (0.36) | KLKB1MAP4K1KDM4EALDH1A1KDM4A | |
| SCHEMBL17663981 | 0.79 | GPR52 (0.38) | KDM5AKDM5BSLC6A4 | |
| SCHEMBL23716441 | 0.72 | KEAP1 (0.38) | L3MBTL1DHFRIDO1KDM4EALDH1A1 | |
| SCHEMBL31416644 | 0.72 | — | — | |
| SCHEMBL29426994 | 0.72 | GABRA1 (0.44) | L3MBTL1IDO1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL539467 | 0.72 | — | — | |
| SCHEMBL43286 | 0.72 | GABRA1 (0.44) | L3MBTL1IDO1KDM4EALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL38660567 | 0.70 | CYP1A2 (0.47) | L3MBTL1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL3790563 | 0.70 | TRPA1 (0.43) | L3MBTL1IDO1KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209732-B1 | SPHINGOSINE-1-PHOSPATE RECEPTOR MODULATORS FOR TREATMENT OF CARDIOPULMONARY DISORDERS | SCRIPPS RESEARCH INST (US) | 2021-08-04 | — | — | EP | disclosed |