Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 1/20 | 0.52 |
| ▸ | HPGDS | O60760 | 1/20 | 0.47 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.45 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21027147 | 0.86 | CCKBR (0.49) | CCKBRHPGDSPIN1HDAC1ERAP2 | |
| Hydrochloric Acid SCHEMBL9196037 | 0.81 | HPGDS (0.56) | CCKBRHPGDSPIN1 | |
| SCHEMBL21119530 | 0.76 | CCKBR (0.60) | CCKBRHDAC3HDAC1HDAC2ERAP2 | |
| SCHEMBL9704537 | 0.76 | DRD4 (0.48) | CCKBRPIN1 | |
| SCHEMBL18803704 | 0.72 | PIN1 (0.59) | CCKBRPIN1HDAC3HDAC1HDAC2 | |
| SCHEMBL29411228 | 0.72 | SLC6A5 (0.45) | — | |
| SCHEMBL21375731 | 0.71 | HDAC1 (0.74) | HDAC3HDAC1HDAC2 | |
| SCHEMBL12706067 | 0.71 | RAB9A (0.65) | CCKBRHDAC3HDAC1HDAC2MEN1 | |
| SCHEMBL16571063 | 0.71 | HDAC3 (0.49) | CCKBRPIN1HDAC3HDAC1HDAC2 | |
| Hydrochloric Acid SCHEMBL21271797 | 0.71 | NR1H4 (0.50) | PIN1ERAP2LNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11078164-B1 | PTEN binding compounds, formulations, and uses thereof | UNIVERSITY OF SOUTH FLORIDA (US) | 2021-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11078164-B1 | PTEN binding compounds, formulations, and uses thereof | PTEN, EYA2, PIK3CA | CCKBR 4710/4885HPGDS 2063/4885PIN1 1849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.