Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 6/20 | 0.38 |
| ▸ | HTR7 | P34969 | 6/20 | 0.38 |
| ▸ | DRD2 | P14416 | 4/20 | 0.36 |
| ▸ | HRH2 | P25021 | 4/20 | 0.34 |
| ▸ | HRH1 | P35367 | 4/20 | 0.34 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.34 |
| ▸ | DRD4 | P21917 | 2/20 | 0.34 |
| ▸ | DRD5 | P21918 | 2/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.34 |
| ▸ | HTR6 | P50406 | 2/20 | 0.34 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26700936 | 0.88 | HTR1A (0.38) | HTR1AHTR7DRD2HRH2HRH1 | |
| SCHEMBL23729305 | 0.86 | HRH2 (0.46) | HTR1AHTR7HRH2HRH1 | |
| SCHEMBL23729306 | 0.85 | HTR7 (0.39) | HTR1AHTR7HRH2HRH1SIGMAR1 | |
| SCHEMBL26700934 | 0.83 | HRH2 (0.40) | HTR1AHTR7DRD2HRH2HRH1 | |
| SCHEMBL26700879 | 0.81 | ALDH1A1 (0.37) | HTR1AHTR7HRH2HRH1SIGMAR1 | |
| SCHEMBL26700958 | 0.79 | HTR7 (0.34) | HTR1AHTR7HRH2HRH1SIGMAR1 | |
| SCHEMBL26700931 | 0.79 | DRD2 (0.41) | DRD2DRD3NPC1 | |
| SCHEMBL23729302 | 0.78 | GNAI3 (0.46) | HTR7DRD2PAOXDRD3NPC1 | |
| SCHEMBL23729789 | 0.77 | ALDH1A1 (0.40) | SIGMAR1CACNA1CNPC1 | |
| SCHEMBL26700788 | 0.76 | ALDH1A1 (0.39) | SIGMAR1CACNA1CNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155321-A2 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |