Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GDA | Q9Y2T3 | 2/20 | 0.49 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.35 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18989874 | 0.79 | GDA (0.47) | GDAKDM4EALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL9387974 | 0.73 | GDA (0.38) | GDAPDE3BPDE3AKDM4EALDH1A1 | |
| SCHEMBL9386888 | 0.72 | GDA (0.37) | GDAPDE3BPDE3AKDM4EALDH1A1 | |
| SCHEMBL874548 | 0.72 | ALDH1A1 (0.39) | GDAALDH1A1NOD1DPP4ADORA2B | |
| SCHEMBL7403405 | 0.71 | GDA (0.40) | GDAKDM4EALDH1A1MAPTNPSR1 | |
| SCHEMBL12323353 | 0.70 | PDE2A (0.33) | PDE3BPDE3AKDM4EALDH1A1MAPT | |
| SCHEMBL6876786 | 0.69 | GAA (0.58) | KDM4EALDH1A1HSD17B10GAANPSR1 | |
| SCHEMBL789315 | 0.68 | NPC1 (0.50) | GDAKDM4EALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL789316 | 0.68 | NPC1 (0.50) | GDAKDM4EALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL12958953 | 0.67 | PNP (0.46) | KDM4EALDH1A1CYP1A2HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250381198-A1 | MIDAZOLAM AND KETAMINE FOR ENHANCED SEDATION | FIFTH THIRD BANK, NATIONAL ASSOCIATION, AS AGENT | 2025-12-18 | — | — | US | disclosed |
| US-20240415848-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR ANESTHESIOLOGICAL APPLICATIONS | FIFTH THIRD BANK, NATIONAL ASSOCIATION, AS AGENT | 2024-12-19 | — | — | US | disclosed |
| US-12083126-B2 | Pharmaceutical compositions and methods for anesthesiological applications | MELT PHARMACEUTICALS, INC. (US) | 2024-09-10 | — | — | US | disclosed |
| US-20240207285-A1 | MIDAZOLAM AND KETAMINE FOR ENHANCED SEDATION | FIFTH THIRD BANK, NATIONAL ASSOCIATION, AS AGENT | 2024-06-27 | — | — | US | disclosed |
| CN-115023503-A | Method for producing closed linear DNA | 泰瑞斯疗法公司 | 2022-09-06 | — | — | CN | disclosed |
| US-20220249510-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR ANESTHESIOLOGICAL APPLICATIONS | FIFTH THIRD BANK, NATIONAL ASSOCIATION, AS AGENT | 2022-08-11 | — | — | US | disclosed |
| US-20210085691-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR ANESTHESIOLOGICAL APPLICATIONS | FIFTH THIRD BANK, NATIONAL ASSOCIATION, AS AGENT | 2021-03-25 | — | — | US | disclosed |
| US-20200297734-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR ANESTHESIOLOGICAL APPLICATIONS | FIFTH THIRD BANK, NATIONAL ASSOCIATION, AS AGENT | 2020-09-24 | — | — | US | disclosed |
| US-10391102-B2 | Pharmaceutical compositions and methods for anesthesiological applications | MELT PHARMACEUTICALS, INC. (US) | 2019-08-27 | — | — | US | disclosed |
| US-20190142841-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR ANESTHESIOLOGICAL APPLICATIONS | HARROW IP, LLC | 2019-05-16 | — | — | US | disclosed |
| EP-3389664-A1 | CAFFEINE INHIBITORS OF MTHFD2 AND USES THEREOF | Raze Therapeutics Inc. (US) | 2018-10-24 | — | — | EP | disclosed |
| US-20180271877-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR ANESTHESIOLOGICAL APPLICATIONS | FIFTH THIRD BANK, NATIONAL ASSOCIATION, AS AGENT | 2018-09-27 | — | — | US | disclosed |
| US-20180177797-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR ANESTHESIOLOGICAL APPLICATIONS | FIFTH THIRD BANK, NATIONAL ASSOCIATION, AS AGENT | 2018-06-28 | — | — | US | disclosed |
| US-20180177796-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR ANESTHESIOLOGICAL APPLICATIONS | FIFTH THIRD BANK, NATIONAL ASSOCIATION, AS AGENT | 2018-06-28 | — | — | US | disclosed |
| US-9918993-B2 | Pharmaceutical compositions for anesthesiological applications | IMPRIMIS PHARMACEUTICALS, INC. (US) | 2018-03-20 | — | — | US | disclosed |
| WO-2017106352-A1 | CAFFEINE INHIBITORS OF MTHFD2 AND USES THEREOF | RAZE THERAPEUTICS, INC. (US) | 2017-06-22 | — | — | WO | disclosed |
| US-20160367566-A1 | PHARMACEUTICAL COMPOSITIONS FOR ANESTHESIOLOGICAL APPLICATIONS | FIFTH THIRD BANK, NATIONAL ASSOCIATION, AS AGENT | 2016-12-22 | — | — | US | disclosed |
| US-8828990-B2 | N-7 substituted purine and pyrazolopyrimine compounds, compositions and methods of use | GENENTECH, INC. (US) | 2014-09-09 | — | — | US | disclosed |
| EP-1301187-A2 | HETEROCYCLIC COMPOUNDS, WHICH ARE INHIBITORS OF THE ENZYME DPP-IV | NOVO NORDISK A/S (DK) | 2003-04-16 | — | — | EP | disclosed |
| WO-2002002560-A2 | PURINE-2,6-DIONES WHICH ARE INHIBITORS OF THE ENZYME DIPEPTIDYL PEPTIDASE IV (DPP-IV) | NOVO NORDISK A/S (DK) | 2002-01-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220249510-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR ANESTHESIOLOGICAL APPLICATIONS | GRIN3A, OPRK1, GRIN2B | GDA 2968/4885PDE3B 1025/4885PDE3A 870/4885 |
| US-20180177797-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR ANESTHESIOLOGICAL APPLICATIONS | GRIN2B, GRIN3A, GABRA5 | GDA 2860/4885PDE3B 1416/4885PDE3A 1280/4885 |
| US-10391102-B2 | Pharmaceutical compositions and methods for anesthesiological applications | GRIN2B, GRIN3A, GABRA5 | GDA 2902/4885PDE3B 1419/4885PDE3A 1291/4885 |
| US-20190142841-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR ANESTHESIOLOGICAL APPLICATIONS | GRIN3A, OPRK1, GRIN2B | GDA 2968/4885PDE3B 1025/4885PDE3A 870/4885 |
| US-20240415848-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR ANESTHESIOLOGICAL APPLICATIONS | GRIN3A, OPRK1, GRIN2B | GDA 2968/4885PDE3B 1025/4885PDE3A 870/4885 |
| US-20240207285-A1 | MIDAZOLAM AND KETAMINE FOR ENHANCED SEDATION | KCNA3, OPRK1, KCNA7 | GDA 3613/4885PDE3B 1417/4885PDE3A 936/4885 |
| US-20160367566-A1 | PHARMACEUTICAL COMPOSITIONS FOR ANESTHESIOLOGICAL APPLICATIONS | GRIN2B, GRIN3A, GABRB1 | GDA 2448/4885PDE3B 772/4885PDE3A 853/4885 |
| US-20200297734-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR ANESTHESIOLOGICAL APPLICATIONS | GRIN3A, OPRK1, GRIN2B | GDA 2968/4885PDE3B 1025/4885PDE3A 870/4885 |
| US-20210085691-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR ANESTHESIOLOGICAL APPLICATIONS | GRIN2B, GRIN3A, GRIN1 | GDA 3080/4885PDE3B 1552/4885PDE3A 1398/4885 |
| US-20250381198-A1 | MIDAZOLAM AND KETAMINE FOR ENHANCED SEDATION | KCNA3, OPRK1, KCNA7 | GDA 3613/4885PDE3B 1417/4885PDE3A 936/4885 |
| US-20180177796-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR ANESTHESIOLOGICAL APPLICATIONS | GRIN2B, GRIN3A, GABRA5 | GDA 2860/4885PDE3B 1416/4885PDE3A 1280/4885 |
| US-20180271877-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR ANESTHESIOLOGICAL APPLICATIONS | GRIN2B, GRIN3A, GABRA5 | GDA 2902/4885PDE3B 1419/4885PDE3A 1291/4885 |
| US-12083126-B2 | Pharmaceutical compositions and methods for anesthesiological applications | GRIN3A, OPRK1, GRIN2B | GDA 2968/4885PDE3B 1025/4885PDE3A 870/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.