Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2253610 | 0.85 | MAPT (0.40) | CES2CES1MEN1KMT2AALDH1A1 | |
| SCHEMBL10126426 | 0.82 | CES2 (0.43) | CES2MEN1KMT2AMAPTNPC1 | |
| SCHEMBL532899 | 0.81 | ALDH1A1 (0.48) | CES2CES1MEN1KMT2AALDH1A1 | |
| SCHEMBL23731520 | 0.80 | ALDH1A1 (0.41) | CES2CES1MEN1KMT2AALDH1A1 | |
| SCHEMBL23731523 | 0.80 | MAPT (0.52) | CES2CES1MEN1KMT2AALDH1A1 | |
| SCHEMBL23731321 | 0.79 | NPC1 (0.51) | CES2CES1MEN1KMT2AALDH1A1 | |
| SCHEMBL7516931 | 0.76 | MAPT (0.32) | MAPTHPGDSMN1; SMN2HDAC3HDAC4 | |
| SCHEMBL775576 | 0.76 | NPC1 (0.64) | CES2CES1MEN1KMT2AALDH1A1 | |
| SCHEMBL23731519 | 0.76 | ALDH1A1 (0.45) | CES2CES1MEN1KMT2AALDH1A1 | |
| SCHEMBL23731518 | 0.75 | LTA4H (0.49) | MEN1KMT2AALDH1A1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11078157-B1 | Compound embodiments that release H2S by reaction with a reactive compound and methods of making and using the same | UNIVERSITY OF OREGON (US) | 2021-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11078157-B1 | Compound embodiments that release H2S by reaction with a reactive compound and methods of making and using the same | CBS, SQOR, QSOX1 | CES2 213/4885CES1 2621/4885MEN1 2168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.