Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6639439 | 0.84 | GLA (0.38) | MAPTHPGDKMT2AALDH1A1 | |
| SCHEMBL450333 | 0.74 | — | — | |
| SCHEMBL3943458 | 0.70 | MAPT (0.49) | MAPTHPGDKMT2AALDH1A1 | |
| SCHEMBL11902792 | 0.68 | MAPT (0.43) | MAPTKMT2A | |
| SCHEMBL7362200 | 0.67 | MAPT (0.42) | MAPT | |
| SCHEMBL6942981 | 0.66 | MAPT (0.60) | MAPTKMT2AALDH1A1 | |
| SCHEMBL3940279 | 0.65 | MAPT (0.48) | MAPTKMT2AALDH1A1 | |
| SCHEMBL2736475 | 0.65 | USP2 (0.33) | MAPTKMT2A | |
| SCHEMBL3643718 | 0.63 | PLA2G7 (0.36) | MAPTHPGDKMT2AALDH1A1 | |
| SCHEMBL20440725 | 0.62 | HDAC4 (0.41) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210238155-A1 | CARBON MONOXIDE PRODRUGS FOR THE TREATMENT OF MEDICAL DISORDERS | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2021-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210238155-A1 | CARBON MONOXIDE PRODRUGS FOR THE TREATMENT OF MEDICAL DISORDERS | PYGL, HMOX2, MB | MAPT 1259/4885HPGD 37/4885KMT2A 3157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.