Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23739966 | 0.99 | KDM4E (0.30) | KDM4E | |
| SCHEMBL23739920 | 0.87 | HTR1A (0.42) | — | |
| SCHEMBL23739669 | 0.85 | DRD2 (0.37) | — | |
| SCHEMBL23739950 | 0.84 | MEN1 (0.35) | KDM4E | |
| SCHEMBL23739671 | 0.84 | ADRA1B (0.40) | — | |
| SCHEMBL23739921 | 0.84 | DRD2 (0.41) | — | |
| SCHEMBL23739905 | 0.84 | DRD2 (0.45) | — | |
| SCHEMBL23739600 | 0.84 | KDM4E (0.40) | KDM4E | |
| SCHEMBL23739929 | 0.83 | DRD2 (0.43) | — | |
| SCHEMBL23739716 | 0.83 | KCNH2 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3862348-A1 | ISOINDOLINE COMPOUND, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2021-08-11 | — | — | EP | disclosed |