SCHEMBL23723262

SCHEMBL23723262

CC(C)(C)OC(=O)NC/C=C(\F)CSc1cccc(C(=O)O)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 1/20 0.48
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38
HPGD P15428 1/20 0.38
HSD17B10 Q99714 1/20 0.38
POLB P06746 2/20 0.36
GAA P10253 2/20 0.36
MAPT P10636 2/20 0.35
ALDH1A1 P00352 3/20 0.34
RAB9A P51151 2/20 0.34
LMNA P02545 1/20 0.34
IDO1 P14902 1/20 0.34
PPARG P37231 3/20 0.34
PPARA Q07869 3/20 0.34
PPARD Q03181 2/20 0.34
NR1H4 Q96RI1 1/20 0.34
BRD4 O60885 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.33
KDM4A O75164 1/20 0.33
MEN1 O00255 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23723265 1.00 APEX1 (0.48) APEX1CYP1A2CYP2C9HPGDHSD17B10
SCHEMBL30633649 0.91 RAB9A (0.38) APEX1HPGDPOLBGAAMAPT
SCHEMBL23723228 0.90 L3MBTL1 (0.45) APEX1POLBGAARAB9ALMNA
SCHEMBL23723229 0.90 L3MBTL1 (0.45) APEX1POLBGAARAB9ALMNA
SCHEMBL26758437 0.88 IDO1 (0.41) HSD17B10MAPTALDH1A1RAB9ALMNA
SCHEMBL23745932 0.87 NQO2 (0.41) CYP1A2CYP2C9POLBGAAMAPT
SCHEMBL23723242 0.87 MAPT (0.43) GAAMAPTALDH1A1RAB9ALMNA
SCHEMBL23723241 0.87 MAPT (0.43) GAAMAPTALDH1A1RAB9ALMNA
SCHEMBL23746020 0.86 CTSK (0.35) CYP1A2CYP2C9POLBGAAALDH1A1
SCHEMBL30633625 0.86 CTSK (0.35) CYP1A2CYP2C9POLBGAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12578335-B2 Bioprobes for lysyl oxidases and uses thereof SYNTARA LIMITED (AU) 2026-03-17 US disclosed
US-20230349907-A1 BIOPROBES FOR LYSYL OXIDASES AND USES THEREOF PHARMAXIS LTD. (AU) 2023-11-02 US disclosed
US-20230349907-A1 BIOPROBES FOR LYSYL OXIDASES AND USES THEREOF PHARMAXIS LTD. (AU) 2023-11-02 US disclosed
US-20230349907-A1 BIOPROBES FOR LYSYL OXIDASES AND USES THEREOF PHARMAXIS LTD. (AU) 2023-11-02 US disclosed
WO-2021155439-A1 BIOPROBES FOR LYSYL OXIDASES AND USES THEREOF PHARMAXIS LTD. (AU) 2021-08-12 WO disclosed
WO-2021155439-A1 BIOPROBES FOR LYSYL OXIDASES AND USES THEREOF PHARMAXIS LTD. (AU) 2021-08-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230349907-A1 BIOPROBES FOR LYSYL OXIDASES AND USES THEREOF MAOB, LOX, LPO APEX1 298/4885CYP1A2 200/4885CYP2C9 383/4885
US-12578335-B2 Bioprobes for lysyl oxidases and uses thereof LOXL1, LOX, LOXL2 APEX1 1156/4885CYP1A2 525/4885CYP2C9 722/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.