SCHEMBL23745972

SCHEMBL23745972

CC(C)(C)OC(=O)NC/C=C(\F)CSc1cccc(CO)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
IDO1 P14902 1/20 0.36
POLB P06746 1/20 0.36
KDM4E B2RXH2 1/20 0.36
GLS O94925 1/20 0.35
PDK1 Q15118 1/20 0.34
PDK2 Q15119 1/20 0.34
PDK3 Q15120 1/20 0.34
PDK4 Q16654 1/20 0.34
CTSS P25774 2/20 0.34
CTSK P43235 1/20 0.34
MAPT P10636 1/20 0.34
ATM Q13315 1/20 0.34
AKT1 P31749 2/20 0.34
SIRT2 Q8IXJ6 1/20 0.34
PPARG P37231 2/20 0.33
PPARA Q07869 1/20 0.33
SYK P43405 1/20 0.33
CTSL P07711 1/20 0.33
CTSB P07858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23745932 0.87 NQO2 (0.41) ALDH1A1IDO1POLBKDM4ECTSK
SCHEMBL30633625 0.86 CTSK (0.35) ALDH1A1IDO1POLBKDM4ECTSK
SCHEMBL23746020 0.86 CTSK (0.35) ALDH1A1IDO1POLBKDM4ECTSK
SCHEMBL30633628 0.85 KDM4E (0.34) ALDH1A1IDO1POLBKDM4EGLS
SCHEMBL26758596 0.85 KDM4E (0.34) ALDH1A1IDO1POLBKDM4EGLS
SCHEMBL26758437 0.85 IDO1 (0.41) ALDH1A1IDO1CTSSCTSKMAPT
SCHEMBL23723262 0.85 APEX1 (0.48) ALDH1A1IDO1POLBMAPTATM
SCHEMBL23723265 0.85 APEX1 (0.48) ALDH1A1IDO1POLBMAPTATM
SCHEMBL30633649 0.84 RAB9A (0.38) ALDH1A1POLBMAPTLMNA
SCHEMBL23723347 0.83 ALDH1A1 (0.41) ALDH1A1POLBKDM4EATMTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12578335-B2 Bioprobes for lysyl oxidases and uses thereof SYNTARA LIMITED (AU) 2026-03-17 US disclosed
US-20230349907-A1 BIOPROBES FOR LYSYL OXIDASES AND USES THEREOF PHARMAXIS LTD. (AU) 2023-11-02 US disclosed
US-20230349907-A1 BIOPROBES FOR LYSYL OXIDASES AND USES THEREOF PHARMAXIS LTD. (AU) 2023-11-02 US disclosed
WO-2021155439-A1 BIOPROBES FOR LYSYL OXIDASES AND USES THEREOF PHARMAXIS LTD. (AU) 2021-08-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230349907-A1 BIOPROBES FOR LYSYL OXIDASES AND USES THEREOF MAOB, LOX, LPO ALDH1A1 367/4885IDO1 100/4885POLB 1226/4885
US-12578335-B2 Bioprobes for lysyl oxidases and uses thereof LOXL1, LOX, LOXL2 ALDH1A1 482/4885IDO1 396/4885POLB 2657/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.