SCHEMBL23745932

SCHEMBL23745932

CC(C)(C)OC(=O)NC/C=C(\F)CSc1cccc(O)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO2 P16083 1/20 0.41
ALDH1A1 P00352 2/20 0.35
KDM4A O75164 1/20 0.34
MEN1 O00255 1/20 0.34
MAPT P10636 1/20 0.34
KMT2A Q03164 1/20 0.34
GAA P10253 1/20 0.34
CTSK P43235 1/20 0.34
SYK P43405 1/20 0.34
POLB P06746 2/20 0.33
MALT1 Q9UDY8 1/20 0.33
IDO1 P14902 1/20 0.33
MAPK1 P28482 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
SIRT2 Q8IXJ6 1/20 0.33
KDM4E B2RXH2 1/20 0.33
ATM Q13315 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23746020 0.88 CTSK (0.35) NQO2ALDH1A1KDM4AGAACTSK
SCHEMBL30633625 0.88 CTSK (0.35) NQO2ALDH1A1KDM4AGAACTSK
SCHEMBL26758437 0.87 IDO1 (0.41) ALDH1A1KDM4AMAPTCTSKSYK
SCHEMBL23745972 0.87 ALDH1A1 (0.36) NQO2ALDH1A1KDM4AMAPTCTSK
SCHEMBL23723262 0.87 APEX1 (0.48) NQO2ALDH1A1KDM4AMEN1MAPT
SCHEMBL23723265 0.87 APEX1 (0.48) NQO2ALDH1A1KDM4AMEN1MAPT
SCHEMBL30633649 0.86 RAB9A (0.38) ALDH1A1MAPTGAAPOLB
SCHEMBL23723267 0.82 KMT2A (0.41) ALDH1A1MEN1MAPTKMT2AGAA
SCHEMBL23723269 0.82 KMT2A (0.41) ALDH1A1MEN1MAPTKMT2AGAA
SCHEMBL21693480 0.81 BRD4 (0.36) ALDH1A1MAPTGAAMALT1IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12578335-B2 Bioprobes for lysyl oxidases and uses thereof SYNTARA LIMITED (AU) 2026-03-17 US disclosed
US-20230349907-A1 BIOPROBES FOR LYSYL OXIDASES AND USES THEREOF PHARMAXIS LTD. (AU) 2023-11-02 US disclosed
US-20230349907-A1 BIOPROBES FOR LYSYL OXIDASES AND USES THEREOF PHARMAXIS LTD. (AU) 2023-11-02 US disclosed
US-20230349907-A1 BIOPROBES FOR LYSYL OXIDASES AND USES THEREOF PHARMAXIS LTD. (AU) 2023-11-02 US disclosed
WO-2021155439-A1 BIOPROBES FOR LYSYL OXIDASES AND USES THEREOF PHARMAXIS LTD. (AU) 2021-08-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230349907-A1 BIOPROBES FOR LYSYL OXIDASES AND USES THEREOF MAOB, LOX, LPO NQO2 254/4885ALDH1A1 367/4885KDM4A 623/4885
US-12578335-B2 Bioprobes for lysyl oxidases and uses thereof LOXL1, LOX, LOXL2 NQO2 1119/4885ALDH1A1 482/4885KDM4A 351/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.