SCHEMBL23748573

SCHEMBL23748573

NC1C=C(c2ccccc2)C=CC1(O)NC(=O)O

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SMYD3 Q9H7B4 1/20 0.32
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23928823 0.82 NFKB1 (0.37) LMNA
SCHEMBL6852873 0.77 THRB (0.33) LMNA
SCHEMBL28716007 0.76 MMP3 (0.31)
SCHEMBL28579116 0.75 LMNA (0.34) LMNA
SCHEMBL28538107 0.75 LMNA (0.34) LMNA
SCHEMBL28874371 0.73 HTT (0.34)
SCHEMBL28652511 0.70 HTT (0.35) LMNA
SCHEMBL27503377 0.69 MAOB (0.34)
SCHEMBL28438018 0.68 LMNA (0.36) LMNA
SCHEMBL11418958 0.68 MAOB (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3863631-A1 PYRIMIDINE AND PYRAZINE HDAC1,2 INHIBITORS Regenacy Pharmaceuticals, Inc. (US) 2021-08-18 EP disclosed