Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.41 |
| ▸ | CHRNA1 | P02708 | 6/20 | 0.41 |
| ▸ | CHRNB1 | P11230 | 6/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 6/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 6/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 6/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 6/20 | 0.41 |
| ▸ | CHRNG | P07510 | 4/20 | 0.41 |
| ▸ | CHRND | Q07001 | 4/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17886590 | 0.86 | OPRL1 (0.50) | CCR1OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL18115648 | 0.79 | ALDH1A1 (0.58) | OPRM1OPRD1OPRK1OPRL1ALDH1A1 | |
| SCHEMBL1155345 | 0.79 | OPRM1 (0.50) | CCR1OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL2463684 | 0.76 | DRD2 (0.36) | CCR1ALDH1A1SLC6A2SLC6A4DRD2 | |
| SCHEMBL21826203 | 0.76 | STS (0.47) | SMN1; SMN2GRIN2B | |
| SCHEMBL31125398 | 0.76 | STS (0.47) | SMN1; SMN2GRIN2B | |
| SCHEMBL28323043 | 0.75 | SLC6A3 (0.50) | CCR1OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL27681431 | 0.75 | SLC6A4 (0.54) | CCR1OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL11560742 | 0.75 | OPRD1 (0.52) | CCR1OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL22209906 | 0.74 | SLC6A3 (0.43) | CCR1SLC6A2SLC6A3SLC6A4CHRNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3863711-A1 | AMINO ACID COMPOUNDS AND METHODS OF USE | Pliant Therapeutics, Inc. (US) | 2021-08-18 | — | — | EP | disclosed |