Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 3/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.31 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.30 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.30 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.30 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23749242 | 0.86 | MAPT (0.39) | PDK2AREGFRMEN1USP2 | |
| SCHEMBL23774775 | 0.86 | RARA (0.34) | PDK2ALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL23764914 | 0.86 | FTO (0.35) | PDK2MEN1USP2ALDH1A1LMNA | |
| SCHEMBL23749244 | 0.81 | CA12 (0.34) | ARMEN1USP2ALDH1A1LMNA | |
| SCHEMBL23749241 | 0.75 | FTO (0.53) | EGFRMEN1USP2ALDH1A1LMNA | |
| SCHEMBL23749240 | 0.74 | ALDH1A1 (0.43) | PDK2ARMEN1USP2ALDH1A1 | |
| SCHEMBL31650879 | 0.71 | SIRT2 (0.40) | SIRT2SIRT1 | |
| SCHEMBL23749243 | 0.71 | MEN1 (0.45) | PDK2ARMEN1USP2ALDH1A1 | |
| SCHEMBL23764878 | 0.70 | ALDH1A1 (0.39) | PDK2MEN1USP2ALDH1A1LMNA | |
| SCHEMBL23764913 | 0.68 | ALDH1A1 (0.41) | PDK2MEN1USP2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230104281-A1 | FLUORESCENT RHODAMINE DYES WITH ENHANCED CELL PERMEABILITY | MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E. V. (DE) | 2023-04-06 | — | — | US | disclosed |
| EP-3865544-A1 | FLUORESCENT RHODAMINE DYES WITH ENHANCED CELL PERMEABILITY | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2021-08-18 | — | — | EP | disclosed |