Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | MMP9 | P14780 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.46 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13624774 | 1.00 | HSD17B10 (0.53) | HSD17B10CYP1A2KMT2AMEN1RXFP1 | |
| SCHEMBL13624876 | 0.82 | TGM2 (0.51) | KMT2AMEN1MAOAMAOBSMN1; SMN2 | |
| SCHEMBL13624994 | 0.82 | TP53 (0.52) | KMT2ARXFP1MMP1MMP2MMP9 | |
| SCHEMBL13624691 | 0.82 | SIGMAR1 (0.49) | KMT2AMEN1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL14981521 | 0.81 | KIF11 (0.50) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL14981678 | 0.81 | GAA (0.46) | HSD17B10CYP1A2MMP1MMP2MMP9 | |
| SCHEMBL10271727 | 0.80 | HSD17B10 (0.61) | HSD17B10CYP1A2KMT2AMEN1RXFP1 | |
| SCHEMBL14981720 | 0.79 | GPR35 (0.35) | HSD17B10KMT2AMEN1PKMSMN1; SMN2 | |
| SCHEMBL14981681 | 0.76 | SYK (0.41) | KCNH2FLT3 | |
| SCHEMBL166848 | 0.76 | HSD17B10 (0.69) | HSD17B10CYP1A2KMT2AMEN1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021156774-A1 | COMBINATION THERAPY FOR TREATING MPS1 | GAIN THERAPEUTICS SA (CH) | 2021-08-12 | — | — | WO | disclosed |