Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 12/20 | 0.36 |
| ▸ | JAK2 | O60674 | 3/20 | 0.35 |
| ▸ | JAK1 | P23458 | 4/20 | 0.34 |
| ▸ | JAK3 | P52333 | 2/20 | 0.34 |
| ▸ | BRDT | Q58F21 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | BRD2 | P25440 | 1/20 | 0.32 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16492684 | 0.81 | KEAP1 (0.41) | PTGS1PTGS2 | |
| SCHEMBL19303545 | 0.79 | BRD4 (0.46) | BRD4JAK2JAK1JAK3PTGS1 | |
| SCHEMBL20290539 | 0.78 | NNMT (0.42) | JAK2JAK3PTGS1PTGS2 | |
| SCHEMBL24435816 | 0.73 | BRD4 (0.45) | BRD4 | |
| SCHEMBL24304320 | 0.73 | BRD4 (0.57) | BRD4JAK2JAK1JAK3BRDT | |
| SCHEMBL25215031 | 0.70 | NOS3 (0.31) | — | |
| SCHEMBL17336598 | 0.69 | RAB9A (0.42) | — | |
| SCHEMBL17336530 | 0.68 | AAK1 (0.42) | BRD4 | |
| SCHEMBL18348353 | 0.67 | MAPK14 (0.35) | — | |
| SCHEMBL24435768 | 0.67 | PTGS1 (0.49) | PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220017507-A1 | PI-Kinase Inhibitors with Anti-Infective Activity | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2022-01-20 | — | — | US | disclosed |
| US-11091472-B2 | PI-kinase inhibitors with anti-infective activity | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11091472-B2 | PI-kinase inhibitors with anti-infective activity | PIP4K2A, PIP5K1A, PIP4K2C | BRD4 265/4885JAK2 729/4885JAK1 180/4885 |
| US-20220017507-A1 | PI-Kinase Inhibitors with Anti-Infective Activity | PIP4K2A, PIP5K1A, PIP4K2C | BRD4 276/4885JAK2 833/4885JAK1 246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.