Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.30 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23770853 | 0.90 | ABL1 (0.34) | WDR5ABL1RETLMNARAB9A | |
| SCHEMBL29464526 | 0.85 | WDR5 (0.33) | WDR5ABL1HTR1AGUCY1A1GUCY1B1 | |
| SCHEMBL19925762 | 0.85 | WDR5 (0.33) | WDR5ABL1HTR1AGUCY1A1GUCY1B1 | |
| SCHEMBL23770466 | 0.83 | CYP1A2 (0.37) | WDR5ABL1HTR1A | |
| SCHEMBL23770452 | 0.82 | PDE10A (0.34) | ABL1FAAHMAPT | |
| SCHEMBL23770757 | 0.81 | MEN1 (0.33) | LMNARAB9AGUCY1A1GUCY1B1MAPT | |
| SCHEMBL23770770 | 0.81 | ADRB2 (0.38) | WDR5ABL1 | |
| SCHEMBL23770508 | 0.80 | ABL1 (0.35) | ABL1RET | |
| SCHEMBL23770463 | 0.80 | BTK (0.34) | ABL1MAPT | |
| SCHEMBL23770841 | 0.78 | MEN1 (0.34) | LMNARAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3504194-B1 | N-(PYRIDIN-2-YL)PYRIDINE-SULFONAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | NOVARTIS AG (CH) | 2021-08-18 | — | — | EP | disclosed |