Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGPAT2 | O15120 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 4/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.32 |
| ▸ | GABRE | P78334 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23770561 | 0.92 | IL2 (0.34) | AGPAT2PDE2AMAPTMCL1IL2 | |
| SCHEMBL23770558 | 0.87 | AGPAT2 (0.40) | AGPAT2ABL1MAPK14 | |
| SCHEMBL23770590 | 0.84 | ADORA2A (0.35) | BACE1LMNA | |
| SCHEMBL23770627 | 0.83 | ADORA2A (0.40) | SMN1; SMN2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL23770626 | 0.83 | TRPV1 (0.35) | AGPAT2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL23770740 | 0.82 | HSD11B1 (0.33) | ABL1 | |
| SCHEMBL23770542 | 0.82 | MPL (0.34) | BACE1NOTUM | |
| SCHEMBL23770715 | 0.81 | AGPAT2 (0.34) | AGPAT2ABL1MAPK14 | |
| SCHEMBL23770732 | 0.81 | NOS3 (0.38) | AGPAT2PDE2AABL1IL2NOTUM | |
| SCHEMBL23770756 | 0.80 | BACE1 (0.36) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3504194-B1 | N-(PYRIDIN-2-YL)PYRIDINE-SULFONAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | NOVARTIS AG (CH) | 2021-08-18 | — | — | EP | disclosed |