Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | CDC7 | O00311 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | ACP1 | P24666 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23770566 | 0.86 | AGPAT2 (0.35) | TRPA1 | |
| SCHEMBL23770740 | 0.85 | HSD11B1 (0.33) | HSD11B1CDC7CDK2AR | |
| SCHEMBL23770551 | 0.85 | PTPN1 (0.36) | TRPA1ALDH1A1AR | |
| SCHEMBL23770604 | 0.83 | DHFR (0.32) | — | |
| SCHEMBL23770684 | 0.83 | ADRB2 (0.36) | ALDH1A1 | |
| SCHEMBL23770544 | 0.82 | S1PR1 (0.33) | CDC7CDK2PTGDR2 | |
| SCHEMBL23770405 | 0.81 | PTPN1 (0.31) | — | |
| SCHEMBL23770666 | 0.80 | KRAS (0.39) | PTGDR2KDM4EALDH1A1AR | |
| SCHEMBL29464398 | 0.80 | HSD11B1 (0.43) | HSD11B1KDM4E | |
| SCHEMBL19968784 | 0.80 | HSD11B1 (0.43) | HSD11B1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3504194-B1 | N-(PYRIDIN-2-YL)PYRIDINE-SULFONAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | NOVARTIS AG (CH) | 2021-08-18 | — | — | EP | disclosed |