SCHEMBL23778652

SCHEMBL23778652

CCCCCCCC(=O)NCCc1c[nH]c(-c2ccc(Cl)cc2)n1

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 2/20 0.48
TRPV1 Q8NER1 4/20 0.46
ALDH1A1 P00352 2/20 0.45
MAPT P10636 2/20 0.45
HSD17B10 Q99714 1/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
HPGD P15428 1/20 0.44
FAAH O00519 2/20 0.43
THRB P10828 1/20 0.42
EPHX2 P34913 1/20 0.42
POLB P06746 1/20 0.41
CNR1 P21554 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23778643 0.99 MTNR1A (0.47) MTNR1ATRPV1ALDH1A1MAPTHSD17B10
SCHEMBL23778733 0.91 THRB (0.45) MTNR1AALDH1A1MAPTHPGDTHRB
SCHEMBL23778699 0.83 CA1 (0.43) ALDH1A1MEN1KMT2AHPGDTHRB
SCHEMBL23778677 0.82 THRB (0.41) ALDH1A1MAPTHSD17B10THRBPOLB
SCHEMBL23778650 0.81 MTNR1A (0.48) MTNR1AMAPTHSD17B10MEN1KMT2A
SCHEMBL23778661 0.81 SMN1; SMN2 (0.41) ALDH1A1MAPTHSD17B10MEN1KMT2A
SCHEMBL23778670 0.81 TP53 (0.46) ALDH1A1MAPTMEN1KMT2ATHRB
SCHEMBL23778656 0.81 KDM4E (0.44) ALDH1A1MAPTHSD17B10HPGDTHRB
SCHEMBL23778721 0.80 ADORA3 (0.45) MTNR1AALDH1A1MAPTHSD17B10MEN1
SCHEMBL23778698 0.80 TP53 (0.41) MAPTMEN1KMT2AHPGDPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12378203-B2 Imidazole compounds, process for the synthesis and uses thereof AHAMMUNE BIOSCIENCES PRIVATE LIMITED (IN) 2025-08-05 US claimed
EP-3873890-A1 NOVEL IMIDAZOLE COMPOUNDS, PROCESS FOR THE SYNTHESIS AND USES THEREOF Ahammune Biosciences Private Limited (IN) 2021-09-08 EP claimed
US-20260001850-A1 NOVEL IMIDAZOLE COMPOUNDS, PROCESS FOR THE SYNTHESIS AND USES THEREOF AHAMMUNE BIOSCIENCES PRIVATE LTD (IN) 2026-01-01 US disclosed
US-12378203-B2 Imidazole compounds, process for the synthesis and uses thereof AHAMMUNE BIOSCIENCES PRIVATE LIMITED (IN) 2025-08-05 US disclosed
US-20210380538-A1 NOVEL IMIDAZOLE COMPOUNDS, PROCESS FOR THE SYNTHESIS AND USES THEREOF AHAMMUNE BIOSCIENCES PRIVATE LTD (IN) 2021-12-09 US disclosed
EP-3873890-A1 NOVEL IMIDAZOLE COMPOUNDS, PROCESS FOR THE SYNTHESIS AND USES THEREOF Ahammune Biosciences Private Limited (IN) 2021-09-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210380538-A1 NOVEL IMIDAZOLE COMPOUNDS, PROCESS FOR THE SYNTHESIS AND USES THEREOF IDO1, IDO2, NFATC1 MTNR1A 1790/4885TRPV1 642/4885ALDH1A1 670/4885
US-20260001850-A1 NOVEL IMIDAZOLE COMPOUNDS, PROCESS FOR THE SYNTHESIS AND USES THEREOF MALT1, ADRM1, CYP11B1 MTNR1A 306/4885TRPV1 781/4885ALDH1A1 2523/4885
US-12378203-B2 Imidazole compounds, process for the synthesis and uses thereof IDO1, IDO2, NFATC1 MTNR1A 2087/4885TRPV1 712/4885ALDH1A1 495/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.