SCHEMBL23778705

SCHEMBL23778705

CCCC(=O)NCCc1c[nH]c(-c2cc(Cl)cc(Cl)c2)n1

nearest known ligand 0.43

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 1/20 0.41
MTNR1A P48039 4/20 0.40
MTNR1B P49286 3/20 0.40
TSHR P16473 2/20 0.40
HSD17B10 Q99714 2/20 0.40
KDM4E B2RXH2 1/20 0.40
POLB P06746 1/20 0.40
MAPT P10636 1/20 0.40
HPGD P15428 2/20 0.39
ALDH1A1 P00352 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23778733 0.88 THRB (0.45) MTNR1ATSHRPOLBMAPTHPGD
SCHEMBL23778729 0.83 CXCR2 (0.39) MTNR1AMTNR1BKDM4EMAPTHPGD
SCHEMBL23778719 0.82 ADORA1 (0.50) MTNR1AMTNR1BTSHRHPGD
SCHEMBL23778721 0.81 ADORA3 (0.45) MTNR1AMTNR1BTSHRHSD17B10KDM4E
SCHEMBL23778706 0.81 HPGD (0.43) GSK3BMTNR1AMTNR1BTSHRHPGD
SCHEMBL23778693 0.81 HPGD (0.58) GSK3BHPGD
SCHEMBL23778643 0.80 MTNR1A (0.47) MTNR1AHSD17B10KDM4EPOLBMAPT
SCHEMBL23778715 0.80 MTNR1A (0.48) GSK3BMTNR1AMTNR1BTSHR
SCHEMBL23778652 0.79 MTNR1A (0.48) MTNR1AHSD17B10POLBMAPTHPGD
SCHEMBL24088772 0.79 STK17B (0.42) TSHRHSD17B10KDM4EMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12378203-B2 Imidazole compounds, process for the synthesis and uses thereof AHAMMUNE BIOSCIENCES PRIVATE LIMITED (IN) 2025-08-05 US claimed
EP-3873890-A1 NOVEL IMIDAZOLE COMPOUNDS, PROCESS FOR THE SYNTHESIS AND USES THEREOF Ahammune Biosciences Private Limited (IN) 2021-09-08 EP claimed
US-20260001850-A1 NOVEL IMIDAZOLE COMPOUNDS, PROCESS FOR THE SYNTHESIS AND USES THEREOF AHAMMUNE BIOSCIENCES PRIVATE LTD (IN) 2026-01-01 US disclosed
US-12378203-B2 Imidazole compounds, process for the synthesis and uses thereof AHAMMUNE BIOSCIENCES PRIVATE LIMITED (IN) 2025-08-05 US disclosed
US-20210380538-A1 NOVEL IMIDAZOLE COMPOUNDS, PROCESS FOR THE SYNTHESIS AND USES THEREOF AHAMMUNE BIOSCIENCES PRIVATE LTD (IN) 2021-12-09 US disclosed
EP-3873890-A1 NOVEL IMIDAZOLE COMPOUNDS, PROCESS FOR THE SYNTHESIS AND USES THEREOF Ahammune Biosciences Private Limited (IN) 2021-09-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210380538-A1 NOVEL IMIDAZOLE COMPOUNDS, PROCESS FOR THE SYNTHESIS AND USES THEREOF IDO1, IDO2, NFATC1 GSK3B 1630/4885MTNR1A 1790/4885MTNR1B 1398/4885
US-20260001850-A1 NOVEL IMIDAZOLE COMPOUNDS, PROCESS FOR THE SYNTHESIS AND USES THEREOF MALT1, ADRM1, CYP11B1 GSK3B 442/4885MTNR1A 306/4885MTNR1B 455/4885
US-12378203-B2 Imidazole compounds, process for the synthesis and uses thereof IDO1, IDO2, NFATC1 GSK3B 1342/4885MTNR1A 2087/4885MTNR1B 1749/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.