SCHEMBL23778693

SCHEMBL23778693

CCCC(=O)NCCc1c[nH]c(-c2ccc(F)cc2)n1

nearest known ligand 0.58

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.58
LMNA P02545 1/20 0.45
ADORA3 P0DMS8 1/20 0.44
ADORA2A P29274 1/20 0.44
ADORA1 P30542 1/20 0.44
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
TGFBR1 P36897 1/20 0.41
GSK3B P49841 1/20 0.41
MPO P05164 1/20 0.41
TP53 P04637 1/20 0.41
SPR P35270 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23778721 0.89 ADORA3 (0.45) HPGDADORA3ADORA1MEN1KMT2A
SCHEMBL23778733 0.88 THRB (0.45) HPGDLMNAADORA3TP53
SCHEMBL23778719 0.88 ADORA1 (0.50) HPGDLMNAADORA3ADORA2AADORA1
SCHEMBL23778706 0.86 HPGD (0.43) HPGDGSK3B
SCHEMBL23778696 0.86 MTNR1A (0.50) LMNA
SCHEMBL23778678 0.85 HPGD (0.40) HPGDTP53
SCHEMBL23778716 0.84 MTNR1A (0.45) HPGDADORA3ADORA2AADORA1GSK3B
SCHEMBL24088855 0.83 LMNA (0.51) HPGDLMNATP53
SCHEMBL23778657 0.83 MTNR1A (0.46) LMNAADORA3ADORA2AADORA1TP53
SCHEMBL23778705 0.81 GSK3B (0.41) HPGDGSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12378203-B2 Imidazole compounds, process for the synthesis and uses thereof AHAMMUNE BIOSCIENCES PRIVATE LIMITED (IN) 2025-08-05 US claimed
EP-3873890-A1 NOVEL IMIDAZOLE COMPOUNDS, PROCESS FOR THE SYNTHESIS AND USES THEREOF Ahammune Biosciences Private Limited (IN) 2021-09-08 EP claimed
US-20260001850-A1 NOVEL IMIDAZOLE COMPOUNDS, PROCESS FOR THE SYNTHESIS AND USES THEREOF AHAMMUNE BIOSCIENCES PRIVATE LTD (IN) 2026-01-01 US disclosed
US-12378203-B2 Imidazole compounds, process for the synthesis and uses thereof AHAMMUNE BIOSCIENCES PRIVATE LIMITED (IN) 2025-08-05 US disclosed
US-20210380538-A1 NOVEL IMIDAZOLE COMPOUNDS, PROCESS FOR THE SYNTHESIS AND USES THEREOF AHAMMUNE BIOSCIENCES PRIVATE LTD (IN) 2021-12-09 US disclosed
EP-3873890-A1 NOVEL IMIDAZOLE COMPOUNDS, PROCESS FOR THE SYNTHESIS AND USES THEREOF Ahammune Biosciences Private Limited (IN) 2021-09-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210380538-A1 NOVEL IMIDAZOLE COMPOUNDS, PROCESS FOR THE SYNTHESIS AND USES THEREOF IDO1, IDO2, NFATC1 HPGD 258/4885LMNA 4399/4885ADORA3 3181/4885
US-20260001850-A1 NOVEL IMIDAZOLE COMPOUNDS, PROCESS FOR THE SYNTHESIS AND USES THEREOF MALT1, ADRM1, CYP11B1 HPGD 2454/4885LMNA 2193/4885ADORA3 747/4885
US-12378203-B2 Imidazole compounds, process for the synthesis and uses thereof IDO1, IDO2, NFATC1 HPGD 190/4885LMNA 4397/4885ADORA3 3044/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.