Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.68 |
| ▸ | CA1 | P00915 | 2/20 | 0.68 |
| ▸ | CTSL | P07711 | 1/20 | 0.59 |
| ▸ | PPARG | P37231 | 1/20 | 0.58 |
| ▸ | PPARA | Q07869 | 1/20 | 0.58 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | CCR1 | P32246 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | FPR2 | P25090 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22687175 | 1.00 | CA2 (0.68) | CA2CA1CTSLPPARGPPARA | |
| SCHEMBL2377937 | 1.00 | CA2 (0.68) | CA2CA1CTSLPPARGPPARA | |
| SCHEMBL10664012 | 1.00 | CA2 (0.68) | CA2CA1CTSLPPARGPPARA | |
| SCHEMBL4678843 | 0.89 | CA2 (0.70) | CA2CA1CTSLPPARGPPARA | |
| SCHEMBL4179270 | 0.87 | CA2 (0.57) | CA2CA1CTSLPPARGPPARA | |
| SCHEMBL4179268 | 0.87 | CA2 (0.57) | CA2CA1CTSLPPARGPPARA | |
| SCHEMBL17140599 | 0.86 | TAS1R3 (0.59) | CA2CA1CTSLALDH1A1RAB9A | |
| SCHEMBL17141100 | 0.86 | TAS1R3 (0.59) | CA2CA1CTSLALDH1A1RAB9A | |
| SCHEMBL22697323 | 0.86 | TAS1R3 (0.60) | CA2CA1CTSLALDH1A1RAB9A | |
| SCHEMBL21274377 | 0.86 | TAS1R3 (0.60) | CA2CA1CTSLALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240390399-A1 | MATERIALS AND METHODS FOR SUPPRESSING AND/OR TREATING BONE RELATED DISEASES AND SYMPTOMS | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2024-11-28 | — | — | US | claimed |
| US-20230330116-A1 | MATERIALS AND METHODS FOR SUPPRESSING AND/OR TREATING BONE RELATED DISEASES AND SYMPTOMS | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2023-10-19 | — | — | US | claimed |
| US-20200368259-A1 | MATERIALS AND METHODS FOR SUPPRESSING AND/OR TREATING BONE RELATED DISEASES AND SYMPTOMS | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2020-11-26 | — | — | US | claimed |
| WO-2019028270-A1 | MATERIALS AND METHODS FOR SUPPRESSING AND/OR TREATING BONE RELATED DISEASES AND SYMPTOMS | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2019-02-07 | — | — | WO | claimed |
| US-20240390399-A1 | MATERIALS AND METHODS FOR SUPPRESSING AND/OR TREATING BONE RELATED DISEASES AND SYMPTOMS | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2024-11-28 | — | — | US | disclosed |
| US-20230330116-A1 | MATERIALS AND METHODS FOR SUPPRESSING AND/OR TREATING BONE RELATED DISEASES AND SYMPTOMS | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2023-10-19 | — | — | US | disclosed |
| US-20230257388-A1 | GRANZYME B DIRECTED IMAGING AND THERAPY | CYTOSITE BIOPHARMA INC. (US) | 2023-08-17 | — | — | US | disclosed |
| US-11672811-B2 | Materials and methods for suppressing and/or treating bone related diseases and symptoms | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2023-06-13 | — | — | US | disclosed |
| US-11667645-B2 | Granzyme B directed imaging and therapy | CYTOSITE BIOPHARMA INC. (US) | 2023-06-06 | — | — | US | disclosed |
| CN-112438905-B | Moisturizing and skin-brightening composition and application thereof | 澳思美日用化工（广州）有限公司 | 2021-09-07 | — | — | CN | disclosed |
| CN-112438905-A | Moisturizing and skin-brightening composition and application thereof | 澳思美日用化工（广州）有限公司 | 2021-03-05 | — | — | CN | disclosed |
| CN-112261939-A | Granzyme B directed imaging and therapy | 塞托赛特生物制药股份有限公司 | 2021-01-22 | — | — | CN | disclosed |
| EP-0134561-B1 | ALPHA-ALLENIC-ALPHA-AMINO ACIDS | SYNTEX (U.S.A.) INC. (US) | 1987-07-08 | — | — | EP | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |
| US-4661510-A | FUNGICIDES | SYNTEX (U.S.A.) INC. (US) | 1987-04-28 | — | — | US | disclosed |
| EP-0074761-B1 | PEPTIDE-TYPE SUBSTRATES USEFUL IN THE QUANTITATIVE DETERMINATION OF ENDOTOXIN | WHITTAKER CORPORATION (US) | 1985-12-27 | — | — | EP | disclosed |
| US-4510241-A | BASED ON AXCTIVATING A PROCLOTTIN ENZYME FROM AN AMOEBA FROM HORSE | MALLINCKRODT, INC. (US) | 1985-04-09 | — | — | US | disclosed |
| EP-0134561-A1 | Alpha-allenic-alpha-amino acids | SYNTEX (U.S.A.) INC. (US) | 1985-03-20 | — | — | EP | disclosed |
| US-4406832-A | Peptide-type substrates useful in the quantitative determination of endotoxin | MALLINCKRODT, INC. (US) | 1983-09-27 | — | — | US | disclosed |
| EP-0074761-A1 | Peptide-type substrates useful in the quantitative determination of endotoxin | WHITTAKER CORPORATION (US) | 1983-03-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200368259-A1 | MATERIALS AND METHODS FOR SUPPRESSING AND/OR TREATING BONE RELATED DISEASES AND SYMPTOMS | SOST, TSG101, BST2 | CA2 1317/4885CA1 1474/4885CTSL 1311/4885 |
| US-20230257388-A1 | GRANZYME B DIRECTED IMAGING AND THERAPY | GZMB, PRF1, CTSB | CA2 1885/4885CA1 1536/4885CTSL 46/4885 |
| US-11672811-B2 | Materials and methods for suppressing and/or treating bone related diseases and symptoms | SOST, TSG101, BST2 | CA2 1317/4885CA1 1474/4885CTSL 1311/4885 |
| US-20240390399-A1 | MATERIALS AND METHODS FOR SUPPRESSING AND/OR TREATING BONE RELATED DISEASES AND SYMPTOMS | SOST, TSG101, ACP3 | CA2 1627/4885CA1 1567/4885CTSL 1143/4885 |
| US-11667645-B2 | Granzyme B directed imaging and therapy | GZMB, PRF1, CTSB | CA2 1885/4885CA1 1536/4885CTSL 46/4885 |
| US-20230330116-A1 | MATERIALS AND METHODS FOR SUPPRESSING AND/OR TREATING BONE RELATED DISEASES AND SYMPTOMS | SOST, TSG101, ACP3 | CA2 1627/4885CA1 1567/4885CTSL 1143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.