SCHEMBL2377994

SCHEMBL2377994

CC(C)c1cc(N)cc(C(C)C)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
HTT P42858 2/20 0.41
GAA P10253 1/20 0.41
ALOX12 P18054 1/20 0.41
HIF1A Q16665 1/20 0.41
TSHR P16473 1/20 0.40
GABRA1 P14867 1/20 0.37
GABRB2 P47870 1/20 0.37
FABP3 P05413 2/20 0.36
FABP4 P15090 2/20 0.36
FABP5 Q01469 1/20 0.34
MEN1 O00255 3/20 0.34
NPC1 O15118 3/20 0.34
MAPT P10636 3/20 0.34
RAB9A P51151 3/20 0.34
KMT2A Q03164 3/20 0.34
POLB P06746 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
SCN4A P35499 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methane SCHEMBL27480899 0.97 ALDH1A1 (0.39) ALDH1A1HTTGAAALOX12HIF1A
SCHEMBL10890708 0.94 ALDH1A1 (0.41) ALDH1A1HTTGAAALOX12HIF1A
Methoxymethane SCHEMBL28134919 0.92 ALDH1A1 (0.37) ALDH1A1HTTGAAALOX12HIF1A
SCHEMBL14267832 0.84 ALDH1A1 (0.60) ALDH1A1HTTGAAALOX12HIF1A
SCHEMBL338867 0.83 GABRA1 (0.46) ALDH1A1HTTGAAALOX12HIF1A
SCHEMBL13491971 0.82 ALDH1A1 (0.39) ALDH1A1HTTGAAALOX12HIF1A
SCHEMBL10931556 0.82 ALDH1A1 (0.43) ALDH1A1HTTGAAALOX12HIF1A
Methane SCHEMBL27482061 0.82 ALDH1A1 (0.57) ALDH1A1HTTGAAALOX12HIF1A
SCHEMBL3791553 0.82 CYP3A4 (0.55) ALDH1A1HTTGAAALOX12HIF1A
SCHEMBL29467095 0.82 CYP3A4 (0.55) ALDH1A1HTTGAAALOX12HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12459925-B2 Sulphonyl urea derivatives as NLRP3 inflammasome modulators NodThera Limited (GB) 2025-11-04 US disclosed
EP-4610287-A1 RESIN COMPOSITION, CURED PRODUCT, PREPREG, METAL FOIL-CLAD LAMINATE, RESIN COMPOSITE SHEET, AND PRINTED WIRING BOARD MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2025-09-03 EP disclosed
EP-4610285-A1 RESIN COMPOSITION, CURED PRODUCT, PREPREG, METAL FOIL-CLAD LAMINATE, RESIN COMPOSITE SHEET, AND PRINTED WIRING BOARD MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2025-09-03 EP disclosed
EP-3728238-B1 SULPHONYL UREA DERIVATIVES AS NLRP3 INFLAMMASOME MODULATORS NODTHERA LTD (GB) 2025-06-18 EP disclosed
CN-120092029-A Resin composition, cured product, prepreg, metal foil-clad laminate, resin composite sheet, and printed wiring board 三菱瓦斯化学株式会社 2025-06-03 CN disclosed
CN-119899377-A Polymaleimide compound, curable composition, cured product, prepreg, circuit board, laminate film, semiconductor sealing material, and semiconductor device DIC株式会社 2025-04-29 CN disclosed
US-20240368129-A1 SULPHONYL UREA DERIVATIVES AS NLRP3 INFLAMMASOME MODULATORS NodThera Limited (GB) 2024-11-07 US disclosed
EP-3862360-B1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2024-07-03 EP disclosed
EP-4395520-A2 LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE SAME Samsung Display Co., Ltd. (KR) 2024-07-03 EP disclosed
EP-4395521-A1 CONDENSED CYCLIC COMPOUND, LIGHT-EMITTING DEVICE COMPRISING THE CONDENSED CYCLIC COMPOUND, AND ELECTRONIC APPARATUS COMPRISING THE LIGHT-EMITTING DEVICE Samsung Display Co., Ltd. (KR) 2024-07-03 EP disclosed
US-4721810-A METAL OXIDE CATALYSTS ETHYL CORPORATION (US) 1988-01-26 US disclosed
EP-0240631-A1 Alkylation of amines and amides ETHYL CORPORATION (US) 1987-10-14 EP disclosed
US-4626592-A WITH A CYCLIC ETHER AND B-SUBGROUP METAL OXIDE ALKYLATION CATALYST ETHYL CORPORATION (US) 1986-12-02 US disclosed
US-4613705-A Catalytic alkylation of aromatic amines with alkanols ETHYL CORPORATION (US) 1986-09-23 US disclosed
US-4605766-A REACTING AROMATIC AMINES WITH ETHERS IN PRESENCE OF CATALYST CONTAINING IRON OXIDE ETHYL CORPORATION (US) 1986-08-12 US disclosed
US-4599449-A POSSIBLE RECOVERY OF UNUSED ALCOHOL ETHYL CORPORATION (US) 1986-07-08 US disclosed
EP-0073277-B1 PROCESS FOR PRODUCING ORTHOALKYLATED AROMATIC AMINES MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1985-07-17 EP disclosed
EP-0148009-A2 Process for the alkylation of aromatic amines and use of the products thereof ETHYL CORPORATION (US) 1985-07-10 EP disclosed
EP-0073277-A1 Process for producing orthoalkylated aromatic amines MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1983-03-09 EP disclosed
US-4351958-A Process for producing orthoalkylated aromatic amine MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1982-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240368129-A1 SULPHONYL UREA DERIVATIVES AS NLRP3 INFLAMMASOME MODULATORS NLRP3, NOD1, IL1B ALDH1A1 612/4885HTT 3752/4885GAA 3359/4885
US-12459925-B2 Sulphonyl urea derivatives as NLRP3 inflammasome modulators NLRP3, NOD1, IL1B ALDH1A1 612/4885HTT 3752/4885GAA 3359/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.