Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22704774 | 0.81 | FTO (0.58) | MAPTLMNAMAOAMAOBGPR55 | |
| SCHEMBL26418475 | 0.78 | MAPK14 (0.41) | MAPTLMNAMAOAMEN1KMT2A | |
| SCHEMBL14462993 | 0.77 | S100A4 (0.42) | MEN1KMT2ATDP1POLBALDH1A1 | |
| SCHEMBL6552460 | 0.74 | ESR1 (0.51) | MAPTLMNAGPR55MEN1KMT2A | |
| SCHEMBL12715262 | 0.73 | MAPT (0.68) | MAPTLMNAGPR55MEN1KMT2A | |
| SCHEMBL7044120 | 0.70 | DRD2 (0.53) | LMNAMAOAMAOBPBRM1DRD2 | |
| SCHEMBL23786319 | 0.70 | HSD17B1 (0.35) | MAOAMAOBPBRM1ESR1ESR2 | |
| SCHEMBL15676305 | 0.69 | MAOA (0.67) | MAPTMAOAMAOBMEN1KMT2A | |
| SCHEMBL30074263 | 0.69 | CFTR (0.48) | MAPTLMNAGPR55MEN1KMT2A | |
| SCHEMBL181563 | 0.69 | CFTR (0.48) | MAPTLMNAGPR55MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11827624-B2 | Covalent immune recruiter compounds for immune cell recognition and associated uses | MCMASTER UNIVERSITY (CA) | 2023-11-28 | — | — | US | disclosed |
| US-11827624-B2 | Covalent immune recruiter compounds for immune cell recognition and associated uses | MCMASTER UNIVERSITY (CA) | 2023-11-28 | — | — | US | disclosed |
| US-20210276981-A1 | COVALENT IMMUNE RECRUITER COMPOUNDS FOR IMMUNE CELL RECOGNITION AND ASSOCIATED USES | MCMASTER UNIVERSITY (CA) | 2021-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11827624-B2 | Covalent immune recruiter compounds for immune cell recognition and associated uses | CD74, CD4, HLA-A | MAPT 875/4885LMNA 3035/4885MAOA 1649/4885 |
| US-20210276981-A1 | COVALENT IMMUNE RECRUITER COMPOUNDS FOR IMMUNE CELL RECOGNITION AND ASSOCIATED USES | CD74, CD4, HLA-A | MAPT 1211/4885LMNA 1224/4885MAOA 1535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.