SCHEMBL238005

SCHEMBL238005

O=CN1C(=O)c2ccccc2C1=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.44
CASP3 P42574 3/20 0.43
CYP1A2 P05177 1/20 0.41
EHMT2 Q96KQ7 1/20 0.41
EHMT1 Q9H9B1 1/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
CDC25B P30305 1/20 0.41
ALDH1A1 P00352 2/20 0.41
CA12 O43570 1/20 0.40
CA9 Q16790 1/20 0.40
GLS O94925 1/20 0.40
MAPT P10636 2/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
PKM P14618 1/20 0.39
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
ALOX12 P18054 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30996374 1.00 POLB (0.44) POLBCASP3CYP1A2EHMT2EHMT1
SCHEMBL20954062 0.81 POLB (0.46) POLBCASP3CYP1A2EHMT2EHMT1
SCHEMBL20210860 0.80 ERCC1 (0.59) CYP1A2MEN1KMT2AALDH1A1MAPT
SCHEMBL7223794 0.77 EHMT2 (0.50) POLBCASP3CYP1A2EHMT2EHMT1
SCHEMBL6330619 0.77 ALDH1A1 (0.45) POLBCASP3CYP1A2EHMT2EHMT1
SCHEMBL23604158 0.77 POLB (0.43) POLBCASP3CYP1A2EHMT2EHMT1
SCHEMBL1553885 0.77 CASP3 (0.46) POLBCASP3CYP1A2EHMT2EHMT1
SCHEMBL2910409 0.77 POLB (0.43) POLBCASP3CYP1A2EHMT2EHMT1
SCHEMBL8119562 0.77 CASP3 (0.46) POLBCASP3CYP1A2EHMT2EHMT1
SCHEMBL35297 0.77 ALDH1A1 (0.48) POLBCASP3CYP1A2EHMT2EHMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5427882-A Deinkable toners, developers XEROX CORPORATION (US) 1995-06-27 US claimed
JP-8062896-A None JP disclosed
JP-3045662-A None JP disclosed
JP-59193125-A None JP disclosed
JP-8170027-A None JP disclosed
US-12029708-B2 Alkoxy compounds for disease treatment ACUCELA INC. (US) 2024-07-09 US disclosed
US-20230218549-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ACUCELA INC. 2023-07-13 US disclosed
US-11446261-B2 Alkoxy compounds for disease treatment ACUCELA INC. (US) 2022-09-20 US disclosed
US-20210238155-A1 CARBON MONOXIDE PRODRUGS FOR THE TREATMENT OF MEDICAL DISORDERS GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2021-08-05 US disclosed
US-20210077427-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ACUCELA INC. 2021-03-18 US disclosed
EP-0062523-A2 Detergent additive compositions and preparations and use thereof in detergent compositions THE PROCTER & GAMBLE COMPANY (US) 1982-10-13 EP disclosed
EP-0051987-A1 Bleach activator compositions, preparation thereof and use in granular detergent compositions THE PROCTER & GAMBLE COMPANY (US) 1982-05-19 EP disclosed
US-4321157-A SILICA OR SILICATE, ORGANIC PEROXY ACID BLEACH PRECURSOR, ALIPHATIC ALCOHOL-ALKYLENE OXIDE CONDENSATE NONIONIC SURFACTANT THE PROCTER & GAMBLE COMPANY (US) 1982-03-23 US disclosed
EP-0034387-A2 Mulls containing chain structure clay suspension aids THE PROCTER & GAMBLE COMPANY (US) 1981-08-26 EP disclosed
EP-0028432-A1 Granular laundry compositions THE PROCTER & GAMBLE COMPANY (US) 1981-05-13 EP disclosed
US-4264466-A LAUNDRY DETERGENTS THE PROCTER & GAMBLE COMPANY (US) 1981-04-28 US disclosed
US-4248928-A TETRAACETYL AKYLENEDIAMINES OR TETRAACETYL GLYCOURIL PEROXY BLEACH PRECURSOR THE PROCTER & GAMBLE COMPANY (US) 1981-02-03 US disclosed
US-4232016-A 3-Fluorobenzodiazepines MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) 1980-11-04 US disclosed
US-4179390-A Laundry additive product THE PROCTER & GAMBLE COMPANY (US) 1979-12-18 US disclosed
US-3982891-A Bleaching and detergent compositions having imide activator and peroxygen bleach COLGATE-PALMOLIVE COMPANY (US) 1976-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12029708-B2 Alkoxy compounds for disease treatment ALDH1A2, CLN6, AGER POLB 1979/4885CASP3 336/4885CYP1A2 2936/4885
US-20210238155-A1 CARBON MONOXIDE PRODRUGS FOR THE TREATMENT OF MEDICAL DISORDERS PYGL, HMOX2, MB POLB 2463/4885CASP3 542/4885CYP1A2 28/4885
US-20210077427-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ALDH1A2, CLN6, AGER POLB 1979/4885CASP3 336/4885CYP1A2 2936/4885
US-20230218549-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ALDH1A2, CLN6, AGER POLB 2057/4885CASP3 319/4885CYP1A2 2835/4885
US-11446261-B2 Alkoxy compounds for disease treatment ALDH1A2, CLN6, AGER POLB 1979/4885CASP3 336/4885CYP1A2 2936/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.