SCHEMBL23817282

SCHEMBL23817282

C=CCC1CCc2[nH]c3ccccc3c2C1=O

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.40
HPGD P15428 1/20 0.40
HSD17B10 Q99714 1/20 0.40
SLC2A1 P11166 1/20 0.39
NR2E1 Q9Y466 1/20 0.39
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
PADI4 Q9UM07 4/20 0.36
CYP1A2 P05177 1/20 0.34
CYP2D6 P10635 1/20 0.34
ALPG P10696 1/20 0.34
CYP2C19 P33261 1/20 0.34
KMT2A Q03164 1/20 0.34
SIGMAR1 Q99720 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7408263 0.79 KMT2A (0.43) TP53HPGDHSD17B10SLC2A1NR2E1
Iodide SCHEMBL7405172 0.78 HPGD (0.41) TP53HPGDHSD17B10SLC2A1NR2E1
SCHEMBL23817260 0.78 NR2E1 (0.41) TP53HPGDHSD17B10SLC2A1NR2E1
SCHEMBL2798203 0.72 KMT2A (0.45) HSD17B10KDM4ESMN1; SMN2CYP1A2CYP2D6
SCHEMBL8903120 0.72 CYP19A1 (0.36) KDM4EALDH1A1CYP1A2CYP2D6CYP2C19
SCHEMBL9597484 0.72 HTR3A (0.39) TP53HPGDHSD17B10SLC2A1NR2E1
SCHEMBL12187142 0.71 HTR2B (0.37) TP53HPGDHSD17B10SLC2A1KDM4E
SCHEMBL19118074 0.71 CYP3A4 (0.42) TP53HPGDHSD17B10SLC2A1CYP1A2
SCHEMBL3994101 0.71 CYP3A4 (0.62) TP53HPGDHSD17B10SLC2A1KDM4E
Hydrochloric Acid SCHEMBL7433749 0.71 HTR6 (0.51) TP53HPGDHSD17B10SLC2A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11708320-B2 Environmentally-friendly hydroazidation of olefins GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2023-07-25 US disclosed
US-20210284601-A1 ENVIRONMENTALLY-FRIENDLY HYDROAZIDATION OF OLEFINS GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2021-09-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11708320-B2 Environmentally-friendly hydroazidation of olefins HAO2, AHR, HMOX1 TP53 1404/4885HPGD 569/4885HSD17B10 841/4885
US-20210284601-A1 ENVIRONMENTALLY-FRIENDLY HYDROAZIDATION OF OLEFINS HAO2, AHR, HMOX1 TP53 1404/4885HPGD 569/4885HSD17B10 841/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.