Carfentanil

Carfentanil

SCHEMBL238456

CCC(=O)N(c1ccccc1)C1(C(=O)OC)CCN(CCc2ccccc2)CC1.[NaH]

nearest known ligand 0.98

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 14/20 0.98
OPRD1 P41143 5/20 0.98
OPRK1 P41145 3/20 0.98
CACNA1C Q13936 1/20 0.76
OPRL1 P41146 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
[11C]-Carfentanil SCHEMBL29374424 0.99 OPRM1 (1.00) OPRM1OPRD1OPRK1CACNA1COPRL1
Carfentanil SCHEMBL116222 0.99 OPRM1 (1.00) OPRM1OPRD1OPRK1CACNA1COPRL1
Carfentanil SCHEMBL4256090 0.98 OPRM1 (0.98) OPRM1OPRD1OPRK1CACNA1COPRL1
Carfentanil SCHEMBL9737212 0.97 OPRM1 (0.96) OPRM1OPRD1OPRK1CACNA1COPRL1
Carfentanil SCHEMBL16444962 0.93 OPRM1 (0.89) OPRM1OPRD1OPRK1CACNA1COPRL1
Carfentanil SCHEMBL4385304 0.93 OPRM1 (0.89) OPRM1OPRD1OPRK1CACNA1COPRL1
SCHEMBL11565358 0.93 OPRM1 (0.88) OPRM1OPRD1OPRK1CACNA1COPRL1
SCHEMBL11562298 0.92 OPRM1 (0.86) OPRM1OPRD1OPRK1CACNA1COPRL1
Hydrochloric Acid SCHEMBL11565447 0.92 OPRM1 (0.86) OPRM1OPRD1OPRK1CACNA1COPRL1
SCHEMBL11565468 0.92 OPRM1 (0.86) OPRM1OPRD1OPRK1CACNA1COPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1633703-B1 ISOTOPICALLY LABELED CHEMICALLY STABLE REAGENTS AND PROCESS FOR THE SYNTHESIS THEREOF PERKINELMER LAS INC (US) 2018-12-26 EP disclosed
US-8987501-B2 Isotopically labeled chemically stable reagents and process for the synthesis thereof PERKINELMER HEALTH SCIENCES, INC. (US) 2015-03-24 US disclosed
US-20130030184-A1 ISOTOPICALLY LABELED CHEMICALLY STABLE REAGENTS AND PROCESS FOR THE SYNTHESIS THEREOF PERKINELMER HEALTH SCIENCES, INC. (US) 2013-01-31 US disclosed
US-8329934-B2 Isotopically labeled chemically stable reagents and process for the synthesis thereof PERKINELMER HEALTH SCIENCES, INC. (US) 2012-12-11 US disclosed
US-20120004413-A1 ISOTOPICALLY LABELED CHEMICALLY STABLE REAGENTS AND PROCESS FOR THE SYNTHESIS THEREOF PERKINELMER HEALTH SCIENCES, INC. (US) 2012-01-05 US disclosed
US-8058464-B2 Isotopically labeled chemically stable reagents and process for the synthesis thereof PERKINELMER HEALTH SCIENCES, INC. (US) 2011-11-15 US disclosed
US-20060205953-A1 Isotopically labeled chemically stable reagents and process for the synthesis thereof PERKIN ELMER LAS, INC. (US) 2006-09-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130030184-A1 ISOTOPICALLY LABELED CHEMICALLY STABLE REAGENTS AND PROCESS FOR THE SYNTHESIS THEREOF ALKBH2, ALKBH3, ALKBH1 OPRM1 716/4885OPRD1 1225/4885OPRK1 2158/4885
US-20120004413-A1 ISOTOPICALLY LABELED CHEMICALLY STABLE REAGENTS AND PROCESS FOR THE SYNTHESIS THEREOF HBG2, ALKBH2, ACVR2B OPRM1 771/4885OPRD1 1237/4885OPRK1 2117/4885
US-20060205953-A1 Isotopically labeled chemically stable reagents and process for the synthesis thereof MRPS23, MRPS22, IPO11 OPRM1 716/4885OPRD1 1171/4885OPRK1 1191/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.