Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23551437 | 0.81 | ALDH1A1 (0.54) | ALDH1A1KMT2AMEN1LMNAMAPT | |
| SCHEMBL23855061 | 0.79 | NPC1 (0.40) | ALDH1A1SMN1; SMN2LMNAMAPTHTT | |
| SCHEMBL23538115 | 0.79 | POLB (0.52) | ALDH1A1SMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL3352477 | 0.78 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL23551502 | 0.78 | CNR2 (0.40) | ALDH1A1SMN1; SMN2KMT2ALMNAMAPT | |
| SCHEMBL3705619 | 0.78 | CNR2 (0.37) | ALDH1A1KMT2AMEN1LMNAMAPT | |
| SCHEMBL29540761 | 0.76 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL22777932 | 0.76 | HTR7 (0.47) | ALDH1A1SMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL29714393 | 0.76 | HTR7 (0.47) | ALDH1A1SMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL13057796 | 0.75 | EGFR (0.39) | ALDH1A1SMN1; SMN2LMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210300912-A1 | ARYL HYDROCARBON RECEPTOR (AHR) AGONISTS AND USES THEREOF | Ikena Oncology, Inc. | 2021-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210300912-A1 | ARYL HYDROCARBON RECEPTOR (AHR) AGONISTS AND USES THEREOF | AHR, ARNT, HCAR1 | ALDH1A1 289/4885SMN1; SMN2 4815/4885KMT2A 1031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.