Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | PLK1 | P53350 | 1/20 | 0.31 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23864370 | 0.90 | LMNA (0.35) | LMNAALDH1A1KDM4EALDH2ALOX12 | |
| SCHEMBL23864246 | 0.85 | TXNRD1 (0.36) | LMNAALDH1A1ALDH2HPGDKMT2A | |
| SCHEMBL23864637 | 0.79 | TXNRD1 (0.37) | LMNAALDH1A1ALDH2HPGDKMT2A | |
| SCHEMBL23864361 | 0.76 | PLA2G1B (0.36) | LMNAALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL23864334 | 0.73 | HPGD (0.43) | LMNAALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL23864366 | 0.71 | MAPT (0.37) | ALDH1A1HPGDKMT2ACYP1A2CYP2C19 | |
| SCHEMBL23864723 | 0.71 | MAPT (0.37) | LMNAALDH1A1HPGDKMT2ACYP1A2 | |
| SCHEMBL23864221 | 0.70 | TXNRD1 (0.38) | ALDH1A1ALDH2KMT2AHDAC6 | |
| SCHEMBL4607284 | 0.67 | KMT2A (0.58) | ALDH1A1KDM4EKMT2AHDAC3HDAC8 | |
| SCHEMBL23810069 | 0.66 | ALDH1A1 (0.44) | LMNAALDH1A1ALOX12HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968330-B1 | COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS | SCRIPPS RESEARCH INST (US) | 2021-09-29 | — | — | EP | disclosed |