Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MT-CO2 | P00403 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23864246 | 0.73 | TXNRD1 (0.36) | HPGDLMNAGAAALDH1A1MT-CO2 | |
| SCHEMBL23864263 | 0.73 | LMNA (0.35) | HPGDLMNAALDH1A1KDM4EKMT2A | |
| SCHEMBL26418434 | 0.72 | EPHX2 (0.56) | LMNAKMT2ACYP1A2CYP2C19MAPT | |
| SCHEMBL23864637 | 0.72 | TXNRD1 (0.37) | HPGDLMNAGAAALDH1A1MT-CO2 | |
| SCHEMBL4607284 | 0.71 | KMT2A (0.58) | GAAL3MBTL1ALDH1A1KDM4EKMT2A | |
| SCHEMBL28308813 | 0.71 | GABRA1 (0.45) | LMNAGAAALDH1A1KMT2A | |
| SCHEMBL23864370 | 0.71 | LMNA (0.35) | HPGDLMNAALDH1A1KDM4EKMT2A | |
| SCHEMBL26417189 | 0.70 | EPHX2 (0.59) | KMT2ACYP1A2CYP2C19MAPTHDAC3 | |
| SCHEMBL23864736 | 0.70 | ALDH1A1 (0.36) | HPGDLMNAGAAALDH1A1KDM4E | |
| SCHEMBL13864006 | 0.69 | TPSAB1 (0.44) | HPGDLMNAALDH1A1HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968330-B1 | COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS | SCRIPPS RESEARCH INST (US) | 2021-09-29 | — | — | EP | disclosed |