Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23864228 | 0.90 | ALDH1A1 (0.40) | ALDH1A1MAPTKMT2AGAAHTT | |
| SCHEMBL23864449 | 0.90 | ALDH1A1 (0.49) | ALDH1A1MAPTKMT2AGAAHTT | |
| SCHEMBL23864623 | 0.85 | ALDH1A1 (0.49) | ALDH1A1MAPTKMT2AGAAHTT | |
| SCHEMBL16127932 | 0.73 | ALOX15 (0.43) | ALDH1A1MAPTKMT2AGAAHTT | |
| SCHEMBL16127941 | 0.73 | ALOX15 (0.43) | ALDH1A1MAPTKMT2AGAAHTT | |
| SCHEMBL23864648 | 0.72 | SMN1; SMN2 (0.40) | ALDH1A1MAPTKMT2ALMNAPOLB | |
| SCHEMBL23864206 | 0.70 | POLB (0.46) | ALDH1A1MAPTLMNAPOLBNPC1 | |
| SCHEMBL21207989 | 0.69 | CES2 (0.41) | ALDH1A1CYP1A2 | |
| SCHEMBL23864722 | 0.69 | ALDH1A1 (0.40) | ALDH1A1KMT2AHTTLMNA | |
| SCHEMBL23864215 | 0.68 | POLB (0.44) | ALDH1A1LMNAPOLBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968330-B1 | COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS | SCRIPPS RESEARCH INST (US) | 2021-09-29 | — | — | EP | disclosed |