Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.44 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16088827 | 0.83 | HTT (0.61) | KMT2AMAPTSMN1; SMN2HTTCYP1A2 | |
| SCHEMBL16088601 | 0.82 | KMT2A (0.51) | KMT2AMAPTSMN1; SMN2HTTCYP1A2 | |
| SCHEMBL23864601 | 0.74 | TRPM4 (0.51) | KMT2AMAPTSMN1; SMN2HTTAVPR2 | |
| SCHEMBL13170059 | 0.72 | ALDH1A1 (0.54) | KMT2AMAPTSMN1; SMN2HTTCYP1A2 | |
| SCHEMBL30962791 | 0.72 | NFKB1 (0.50) | KMT2ASMN1; SMN2HPGDPPARGMEN1 | |
| SCHEMBL29758005 | 0.71 | GPR35 (0.69) | KMT2AMAPTSMN1; SMN2HTTMEN1 | |
| SCHEMBL11568751 | 0.71 | GPR35 (0.69) | KMT2AMAPTSMN1; SMN2HTTMEN1 | |
| SCHEMBL9694316 | 0.70 | CYP1A2 (0.48) | KMT2AMAPTSMN1; SMN2CYP1A2HPGD | |
| SCHEMBL23486868 | 0.70 | PDK1 (0.46) | KMT2AMAPTSMN1; SMN2HTTCYP1A2 | |
| SCHEMBL31703290 | 0.70 | ALDH1A1 (0.55) | KMT2AMAPTSMN1; SMN2HTTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968330-B1 | COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS | SCRIPPS RESEARCH INST (US) | 2021-09-29 | — | — | EP | disclosed |