Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGM | P11217 | 10/20 | 0.51 |
| ▸ | ACHE | P22303 | 3/20 | 0.50 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.47 |
| ▸ | CDK2 | P24941 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23867575 | 0.86 | PYGM (0.51) | PYGMCCNE1CDK2ALDH1A1HPGD | |
| SCHEMBL23867514 | 0.85 | POLB (0.50) | ACHEALDH1A1SMN1; SMN2 | |
| SCHEMBL23867574 | 0.80 | PYGM (0.53) | PYGMHPGD | |
| SCHEMBL23867572 | 0.75 | ACHE (0.48) | ACHECCNE1CDK2 | |
| SCHEMBL23867508 | 0.75 | ALDH1A1 (0.55) | PYGMCCNE1CDK2ALDH1A1HPGD | |
| SCHEMBL23867475 | 0.73 | POLB (0.55) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL23867512 | 0.71 | ACHE (0.50) | ACHECCNE1CDK2 | |
| SCHEMBL23867479 | 0.71 | POLB (0.49) | ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL23867506 | 0.70 | ACHE (0.43) | ACHECCNE1CDK2ALDH1A1HPGD | |
| SCHEMBL23867515 | 0.70 | POLB (0.47) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021195279-A2 | SMALL MOLECULE INHIBITORS OF ONCOGENIC CHD1L WITH PRECLINICAL ACTIVITY AGAINST COLORECTAL CANCER | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2021-09-30 | — | — | WO | disclosed |