SCHEMBL238719

SCHEMBL238719

CCCC[Si](C)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.33
ADRB1 P08588 1/20 0.33
ADRB3 P13945 1/20 0.33
TSHR P16473 2/20 0.32
LMNA P02545 1/20 0.32
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20466371 0.93
SCHEMBL6031408 0.93 TSHR (0.38) TSHRLMNATHRB
SCHEMBL728053 0.92 TSHR (0.35) ADRB2ADRB1ADRB3TSHRLMNA
SCHEMBL10001359 0.91
SCHEMBL727830 0.90 TSHR (0.40) TSHRLMNATHRB
SCHEMBL5711705 0.90 TSHR (0.40) TSHRLMNATHRB
SCHEMBL11926993 0.90 TSHR (0.40) TSHRLMNATHRB
SCHEMBL727806 0.90 TSHR (0.40) TSHRLMNATHRB
SCHEMBL1915388 0.90 TSHR (0.40) TSHRLMNATHRB
SCHEMBL21114738 0.90 TSHR (0.40) TSHRLMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 573 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101360476-B Swollen silicone composition, method of making, and article thereof MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2015-08-05 CN claimed
JP-2011527341-A 2011-10-27 JP claimed
EP-2380556-A1 Cosmetic composition comprising a volatile fatty phase L'Oréal (FR) 2011-10-26 EP claimed
US-8017687-B2 Swollen silicone composition and process of producing same MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2011-09-13 US claimed
EP-2296667-A2 SILICONE COMPOSITION Momentive Performance Materials Inc. (US) 2011-03-23 EP claimed
EP-2228053-A1 Swollen silicone composition and process of producing same Momentive Performance Materials Inc. (US) 2010-09-15 EP claimed
JP-2010515566-A 2010-05-13 JP claimed
WO-2010005538-A2 SILICONE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2010-01-14 WO claimed
US-20100003201-A1 Silicone composition MOMENTIVE PERFORMANCE MATERIALS, INC. 2010-01-07 US claimed
EP-2108028-A2 METHOD OF APPLYING A COMPOSITION Momentive Performance Materials Inc. (US) 2009-10-14 EP claimed
EP-1704850-A2 COMPOSITION FOR COATING KERATIN FIBRES, COMPRISING a continuous aqueous phase and at least one volatile oil L'OREAL (FR) 2006-09-27 EP claimed
EP-1472263-B1 USE OF SILOXANES AS EVAPORABLE SUPPORTS GE BAYER SILICONES GMBH & CO (DE) 2006-08-30 EP claimed
WO-2006013412-A1 COSMETIC COMPOSITION COMPRISING AN APOLAR WAX AND AN ALKYLTRISILOXANE L'OREAL (FR) 2006-02-09 WO claimed
WO-2006013411-A1 COSMETIC COMPOSITION FOR KERATIN FIBERS COMPRISING AN ALKYLTRISILOXANE L'OREAL (FR) 2006-02-09 WO claimed
WO-2006013413-A1 COSMETIC COMPOSITION COMPRISING A VOLATILE LINEAR ALKYLTRISILOXANE L'OREAL (FR) 2006-02-09 WO claimed
WO-2006013415-A1 COSMETIC COMPOSITION COMPRISING A CYCLIC SILICONE AND AN ALKYLTRISILOXANE L'OREAL (FR) 2006-02-09 WO claimed
EP-1620068-A1 COSMETIC COMPOSITION COMPRISING A VOLATILE FATTY PHASE L'OREAL (FR) 2006-02-01 EP claimed
US-20050069564-A1 Use of siloxanes as evaporable supports MOMENTIVE PERFORMANCE MATERIALS INC. 2005-03-31 US claimed
WO-2004087077-A1 COSMETIC COMPOSITION COMPRISING A VOLATILE FATTY PHASE L'OREAL (FR) 2004-10-14 WO claimed
US-20040197284-A1 Cosmetic composition comprising a volatile fatty phase L'OREAL S.A. (FR) 2004-10-07 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100003201-A1 Silicone composition CUTA, SMURF1, MMS19 ADRB2 4812/4885ADRB1 4805/4885ADRB3 4675/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.