Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552278 | 0.81 | HMOX1 (0.48) | SMN1; SMN2HMOX1KEAP1L3MBTL1GAA | |
| SCHEMBL497371 | 0.75 | KEAP1 (0.73) | SMN1; SMN2RAB9AKEAP1L3MBTL1MAPT | |
| SCHEMBL40440 | 0.74 | KMT2A (0.67) | SMN1; SMN2RAB9AL3MBTL1MEN1USP2 | |
| SCHEMBL1269478 | 0.74 | RAB9A (0.42) | SMN1; SMN2RAB9AMEN1GAAKMT2A | |
| SCHEMBL10015377 | 0.74 | SMN1; SMN2 (0.41) | SMN1; SMN2RAB9AMEN1GAAMAPT | |
| SCHEMBL13781407 | 0.74 | HMOX1 (0.54) | HMOX1KEAP1L3MBTL1TDP1ALDH1A1 | |
| SCHEMBL107423 | 0.73 | KEAP1 (0.70) | SMN1; SMN2RAB9AKEAP1L3MBTL1MAPT | |
| SCHEMBL712597 | 0.73 | KEAP1 (0.70) | SMN1; SMN2KEAP1L3MBTL1MAPTHTT | |
| Bicarbonate SCHEMBL25171118 | 0.73 | POLB (0.64) | SMN1; SMN2L3MBTL1MEN1GAAKMT2A | |
| SCHEMBL12001993 | 0.72 | KEAP1 (0.61) | SMN1; SMN2KEAP1L3MBTL1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021195671-A1 | PROCESS FOR PREPARING TRIENTINE DIHYDROCHLORIDE | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2021-09-30 | — | — | WO | disclosed |