SCHEMBL23877359

SCHEMBL23877359

CC1=CC(O/C=C(/C(=O)O)C2CCc3c(C)cccc32)OC1=O

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 8/20 0.39
FFAR1 O14842 1/20 0.33
CMA1 P23946 1/20 0.33
ADRA2A P08913 1/20 0.30
ADRA2B P18089 1/20 0.30
ADRA2C P18825 1/20 0.30
ADRA1D P25100 1/20 0.30
ADRA1A P35348 1/20 0.30
ADRA1B P35368 1/20 0.30
PDE10A Q9Y233 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23877360 0.88 CMA1 (0.37) NFE2L2FFAR1CMA1
SCHEMBL21538770 0.88 NFE2L2 (0.37) NFE2L2FFAR1PDE10A
SCHEMBL23877351 0.85 NFE2L2 (0.40) NFE2L2
SCHEMBL23877358 0.79 NFE2L2 (0.37) NFE2L2
SCHEMBL19984938 0.79 FFAR1 (0.34) NFE2L2FFAR1
SCHEMBL23877362 0.78 NFE2L2 (0.39) NFE2L2
SCHEMBL23877357 0.78 NFE2L2 (0.38) NFE2L2
SCHEMBL19984939 0.77 FFAR1 (0.38) NFE2L2FFAR1CMA1
SCHEMBL19984924 0.75 PIN1 (0.41) NFE2L2
SCHEMBL19985039 0.74 NFE2L2 (0.39) NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11136292-B2 Plant growth regulator compounds SYNGENTA PARTICIPATIONS AG (CH) 2021-10-05 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11136292-B2 Plant growth regulator compounds FGF1, MST1, CDC20 NFE2L2 2365/4885FFAR1 2309/4885CMA1 3384/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.