SCHEMBL23879673

SCHEMBL23879673

Cc1cccc(C)c1-c1cccc(-c2cc(C(C)C)ccn2)c1

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.47
GRM5 P41594 1/20 0.40
ASIC3 Q9UHC3 2/20 0.37
CYP2A6 P11509 1/20 0.36
FFAR1 O14842 4/20 0.35
MAPKAPK2 P49137 3/20 0.35
JAK2 O60674 2/20 0.35
HTR7 P34969 1/20 0.35
PIM1 P11309 1/20 0.34
SRC P12931 1/20 0.34
TGFBR1 P36897 1/20 0.34
CTSS P25774 1/20 0.33
CTSK P43235 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17234420 0.83 ATP1A1 (0.45) ASIC3MAPKAPK2TGFBR1
SCHEMBL17426496 0.81 TGFBR1 (0.43) BRD4GRM5ASIC3CYP2A6MAPKAPK2
SCHEMBL14054103 0.79 ASIC3 (0.53) ASIC3CYP2A6MAPKAPK2HTR7PIM1
SCHEMBL17426498 0.78 IDO1 (0.41) GRM5CTSSCTSK
SCHEMBL2609361 0.78 PIM1 (0.48) GRM5MAPKAPK2PIM1TGFBR1
SCHEMBL15340927 0.78 LDHB (0.49) PIM1
Hydrochloric Acid SCHEMBL28148517 0.77 ASIC3 (0.52) ASIC3CYP2A6MAPKAPK2HTR7PIM1
SCHEMBL23879668 0.77 LMNA (0.49) PIM1TGFBR1
SCHEMBL24358706 0.76 RXRA (0.55)
SCHEMBL25456048 0.76 ASIC3 (0.50) ASIC3MAPKAPK2HTR7TGFBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11139443-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-10-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11139443-B2 Organic electroluminescent materials and devices ICOSLG, ORC3, OR10J3 BRD4 964/4885GRM5 647/4885ASIC3 484/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.