Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 12/20 | 0.41 |
| ▸ | PLK3 | Q9H4B4 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9501895 | 0.85 | HTT (0.46) | PLK1PLK3L3MBTL1GAATDP1 | |
| SCHEMBL23891675 | 0.84 | GAA (0.41) | GAARARBTHRATHRBHTT | |
| SCHEMBL2010661 | 0.79 | L3MBTL1 (0.49) | L3MBTL1GAATDP1THRATHRB | |
| SCHEMBL28382016 | 0.78 | HTT (0.57) | L3MBTL1GAATDP1THRATHRB | |
| SCHEMBL29175153 | 0.77 | MAOA (0.50) | L3MBTL1TDP1HTT | |
| SCHEMBL19042193 | 0.77 | L3MBTL1 (0.46) | L3MBTL1TDP1THRATHRBHTT | |
| SCHEMBL23891581 | 0.77 | HTR7 (0.45) | GAARARB | |
| SCHEMBL23891535 | 0.76 | TAS1R3 (0.35) | TDP1HTT | |
| Heptane SCHEMBL11441128 | 0.76 | RARB (0.61) | PLK1PLK3RARB | |
| SCHEMBL4451530 | 0.75 | THRA (0.45) | PLK1PLK3L3MBTL1GAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3889138-A1 | HISTONE ACETYLASE P300 INHIBITOR AND USE THEREOF | Hinova Pharmaceuticals Inc. (CN) | 2021-10-06 | — | — | EP | disclosed |