SCHEMBL23891761

SCHEMBL23891761

CC(=O)CCC(C)C1CCC(C)(F)CC1

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NR1H4 Q96RI1 4/20 0.36
GPBAR1 Q8TDU6 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23891717 0.83
SCHEMBL6567540 0.78 ALDH1A1 (0.36) NR1H4
SCHEMBL12019905 0.75 ALDH1A1 (0.33) NR1H4
SCHEMBL23891762 0.71 CTSK (0.34)
SCHEMBL23178065 0.68 VDR (0.32) NR1H4GPBAR1
SCHEMBL25998265 0.67
SCHEMBL4762376 0.67
SCHEMBL25162340 0.67
SCHEMBL5967361 0.66 GABRP (0.48) GPBAR1
SCHEMBL19386547 0.66 HSD11B1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3889138-A1 HISTONE ACETYLASE P300 INHIBITOR AND USE THEREOF Hinova Pharmaceuticals Inc. (CN) 2021-10-06 EP disclosed