Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.46 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 5/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19911192 | 0.85 | ALDH1A1 (0.41) | ZDHHC20ZDHHC2ALDH1A1TDP1MAPK1 | |
| SCHEMBL38788 | 0.84 | ZDHHC20 (0.57) | ZDHHC20ZDHHC2ALDH1A1TDP1MAPK1 | |
| SCHEMBL20061022 | 0.80 | ZDHHC20 (0.42) | ZDHHC20ZDHHC2ALDH1A1TDP1MAPK1 | |
| SCHEMBL20061023 | 0.79 | ZDHHC20 (0.45) | ZDHHC20ZDHHC2ALDH1A1TDP1MAPK1 | |
| SCHEMBL19915461 | 0.78 | ALDH1A1 (0.35) | ZDHHC20ZDHHC2ALDH1A1TDP1MAPK1 | |
| SCHEMBL35903 | 0.78 | ZDHHC20 (0.60) | ZDHHC20ZDHHC2ALDH1A1TDP1MAPK1 | |
| SCHEMBL23901259 | 0.77 | ADRA1A (0.58) | MAPK1PRMT1KDM4EL3MBTL1KDM4A | |
| SCHEMBL19915462 | 0.77 | ALDH1A1 (0.42) | ZDHHC20ZDHHC2ALDH1A1TDP1MAPK1 | |
| SCHEMBL20063322 | 0.77 | ZDHHC20 (0.41) | ZDHHC20ZDHHC2ALDH1A1TDP1MAPK1 | |
| SCHEMBL20194270 | 0.77 | ZDHHC20 (0.41) | ZDHHC20ZDHHC2ALDH1A1TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018086139-A1 | CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LIKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS | HANGZHOU DAC BIOTECH CO., LTD (CN) | 2018-05-17 | — | — | WO | disclosed |