Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29516647 | 0.95 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2LMNAKDM4ETSHR | |
| SCHEMBL22705629 | 0.89 | LMNA (0.56) | ALDH1A1SMN1; SMN2LMNAKDM4ETSHR | |
| SCHEMBL25442326 | 0.86 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2LMNAKDM4ETSHR | |
| SCHEMBL23903336 | 0.84 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2LMNAKDM4ETSHR | |
| Hydrochloric Acid SCHEMBL7824677 | 0.83 | SIGMAR1 (0.47) | ALDH1A1SMN1; SMN2LMNAKDM4ETSHR | |
| SCHEMBL24597769 | 0.83 | ALDH1A1 (0.71) | ALDH1A1SMN1; SMN2LMNAKDM4ETSHR | |
| SCHEMBL3567407 | 0.83 | NPSR1 (0.56) | ALDH1A1SMN1; SMN2LMNAKDM4ETSHR | |
| SCHEMBL4285382 | 0.82 | GAA (0.50) | ALDH1A1SMN1; SMN2LMNANPSR1MAPT | |
| SCHEMBL25442179 | 0.82 | KMT2A (0.45) | ALDH1A1SMN1; SMN2LMNAHSD11B1NPSR1 | |
| SCHEMBL8020083 | 0.80 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2LMNAKDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230142739-A1 | PROTEIN-PROTEIN INTERACTION STABILIZERS | UNIV CALIFORNIA (US) | 2023-05-11 | — | — | US | disclosed |
| WO-2021203016-A2 | PROTEIN-PROTEIN INTERACTION STABILIZERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-10-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230142739-A1 | PROTEIN-PROTEIN INTERACTION STABILIZERS | HSPBP1, HSPA8, HSPH1 | ALDH1A1 3889/4885SMN1; SMN2 1672/4885LMNA 2827/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.