Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 8/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 7/20 | 0.53 |
| ▸ | ADRA1B | P35368 | 6/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.47 |
| ▸ | HRH1 | P35367 | 2/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | HTR2B | P41595 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23904680 | 1.00 | ADRA1A (0.53) | ADRA1AADRA1DADRA1BKDM4ETDP1 | |
| SCHEMBL23912946 | 0.89 | ADRA1A (0.54) | ADRA1AADRA1DADRA1BKDM4ETDP1 | |
| SCHEMBL18902791 | 0.81 | HTR1B (0.57) | ADRA1AADRA1DADRA1BKDM4ETDP1 | |
| SCHEMBL23912875 | 0.76 | LTA4H (0.48) | ADRA1AADRA1DADRA1BKDM4EHTT | |
| SCHEMBL12840659 | 0.75 | L3MBTL1 (0.61) | KDM4ETDP1HTTALDH1A1PKM | |
| SCHEMBL23912992 | 0.72 | LTA4H (0.53) | ADRA1AADRA1DADRA1BKDM4EHTT | |
| SCHEMBL23904672 | 0.71 | KDM4E (0.40) | ADRA1AADRA1DADRA1BKDM4ETDP1 | |
| SCHEMBL23904670 | 0.71 | KDM4E (0.40) | ADRA1AADRA1DADRA1BKDM4ETDP1 | |
| SCHEMBL23904673 | 0.70 | KDM4E (0.38) | ADRA1AADRA1DADRA1BKDM4ETDP1 | |
| SCHEMBL23904676 | 0.70 | KDM4E (0.38) | ADRA1AADRA1DADRA1BKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892615-A1 | PROCESS FOR THE PREPARATION OF SILODOSIN | Minakem (FR) | 2021-10-13 | — | — | EP | disclosed |