Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GGT1 | P19440 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27669499 | 0.80 | ALDH1A1 (0.46) | TDP1KMT2AMEN1ALDH1A1CYP1A2 | |
| SCHEMBL3293803 | 0.77 | LMNA (0.38) | TDP1KMT2AMAPTMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6214815 | 0.75 | LMNA (0.36) | TDP1KMT2AMEN1ALDH1A1CYP1A2 | |
| SCHEMBL21035141 | 0.75 | ALDH1A1 (0.45) | TDP1ALDH1A1CYP1A2 | |
| SCHEMBL23393881 | 0.73 | LMNA (0.30) | — | |
| SCHEMBL24691959 | 0.72 | ACLY (0.46) | TDP1KMT2AMAPTGGT1MEN1 | |
| Trifluoroacetic Acid SCHEMBL4530228 | 0.71 | NOS1 (0.36) | KMT2AGGT1MEN1ALDH1A1CYP1A2 | |
| SCHEMBL17424317 | 0.71 | — | — | |
| SCHEMBL15340969 | 0.71 | ACLY (0.39) | TDP1KMT2AMAPTGGT1ALDH1A1 | |
| SCHEMBL232206 | 0.70 | KDM4E (0.36) | TDP1KMT2AMEN1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021201577-A1 | HMG-COA REDUCTASE DEGRADATION INDUCING COMPOUND | UPPTHERA (KR) | 2021-10-07 | — | — | WO | disclosed |