SCHEMBL23905762

SCHEMBL23905762

C=Cc1nc2c(OC3CC3)cc(C)cc2s1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23905759 0.79 NPC1 (0.38) HSD17B10
SCHEMBL24448475 0.78 UBE2M (0.34) HSD17B10
SCHEMBL23905552 0.68 NPC1 (0.38) HSD17B10
SCHEMBL23958594 0.66 CCR1 (0.44)
SCHEMBL20064470 0.65 POLB (0.32)
SCHEMBL23905239 0.63 ROCK2 (0.40) HSD17B10
SCHEMBL23905312 0.63 MCHR1 (0.39)
SCHEMBL24345434 0.62 CYP3A4 (0.38) HSD17B10
SCHEMBL13458048 0.62 RAB9A (0.56)
SCHEMBL23905323 0.62 SYK (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021198981-A1 ANTIVIRAL COMPOUNDS AND USES THEREOF Janssen Biopharma, Inc. (US) 2021-10-07 WO disclosed