Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23904715 | 0.81 | MAOA (0.38) | MAOAMAOBSMN1; SMN2LMNAPTBP1 | |
| SCHEMBL23904804 | 0.81 | MAOA (0.38) | MAOAMAOBSMN1; SMN2LMNAPTBP1 | |
| SCHEMBL23958935 | 0.79 | MAOA (0.37) | MAOAMAOBSMN1; SMN2LMNAPTBP1 | |
| SCHEMBL18809492 | 0.70 | LMNA (0.41) | MAOAMAOBSMN1; SMN2LMNAPTBP1 | |
| SCHEMBL21013602 | 0.68 | MAOA (0.45) | MAOAMAOBSMN1; SMN2LMNAPTBP1 | |
| SCHEMBL18944664 | 0.67 | ATM (0.42) | SMN1; SMN2LMNAPTBP1POLBGAA | |
| SCHEMBL28451524 | 0.65 | MAOB (0.39) | MAOAMAOBSMN1; SMN2LMNAPTBP1 | |
| SCHEMBL25488741 | 0.64 | HDAC3 (0.37) | MAOAMAOBSMN1; SMN2LMNAPTBP1 | |
| SCHEMBL30513041 | 0.64 | CA1 (0.53) | SMN1; SMN2POLBKMT2ANPC1RAB9A | |
| SCHEMBL23958873 | 0.64 | CES2 (0.41) | MAOAMAOBPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |