Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.37 |
| ▸ | MAOB | P27338 | 4/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23904715 | 0.84 | MAOA (0.38) | MAOAMAOBHTR7LMNAPTBP1 | |
| SCHEMBL23958937 | 0.79 | CES2 (0.37) | MAOAMAOBLMNAPTBP1SMN1; SMN2 | |
| SCHEMBL23905794 | 0.79 | MAOA (0.39) | MAOAMAOBHTR7LMNAPTBP1 | |
| SCHEMBL18944664 | 0.73 | ATM (0.42) | HTR7LMNAPTBP1SMN1; SMN2POLB | |
| SCHEMBL18809492 | 0.69 | LMNA (0.41) | MAOAMAOBHTR7LMNAPTBP1 | |
| SCHEMBL27468936 | 0.67 | CES2 (0.48) | MAOAMAOBCES2CES1PTPN1 | |
| SCHEMBL25488741 | 0.67 | HDAC3 (0.37) | MAOAMAOBHTR7LMNAPTBP1 | |
| SCHEMBL23958873 | 0.67 | CES2 (0.41) | MAOAMAOBPOLBCES2CES1 | |
| SCHEMBL10413993 | 0.66 | MAOA (0.55) | MAOAMAOBHTR7LMNAPTBP1 | |
| SCHEMBL23195560 | 0.66 | ATM (0.42) | MAOAMAOBLMNASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |